Publications by authors named "Noel D D'Angelo"

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Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK).
Adrian L Smith, Kristin L Andrews, Holger Beckmann, Steven F Bellon, Pedro J Beltran, Noel D D'Angelo

J Med Chem· February 2015

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Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511.
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, Shon K Booker, Sean Caenepeel, Noel D D'Angelo

J Med Chem· September 2012

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Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases.
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, Shon K Booker, Victor J Cee

J Med Chem· June 2012

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Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone series.
Longbin Liu, Mark H Norman, Matthew Lee, Ning Xi, Aaron Siegmund, Noel D D'Angelo

J Med Chem· March 2012

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Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives.
Mark H Norman, Longbin Liu, Matthew Lee, Ning Xi, Ingrid Fellows, Noel D D'Angelo

J Med Chem· March 2012

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Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors.
Noel D D'Angelo, Tae-Seong Kim, Kristin Andrews, Shon K Booker, Sean Caenepeel

J Med Chem· March 2011

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Design, synthesis, and biological evaluation of potent c-Met inhibitors.
Noel D D'Angelo, Steven F Bellon, Shon K Booker, Yuan Cheng, Angela Coxon

J Med Chem· September 2008

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