Publications by authors named "Norah G Verbout"

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Safety and tolerability of the protein C activator AB002 in end-stage renal disease patients on hemodialysis: a randomized phase 2 trial.
Norah G Verbout, Christina U Lorentz, Brandon D Markway, Michael Wallisch, Thomas C Marbury

Commun Med (Lond)· July 2024

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Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis.
Norah G Verbout, Weiping Su, Peter Pham, Kelley R Jordan, Tia C L Kohs

Am J Physiol Cell Physiol· January 2024

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Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice.
Tia C L Kohs, Meghan E Fallon, Ethan C Oseas, Laura D Healy, Erik I Tucker, Norah G Verbout

Metab Brain Dis· October 2023

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E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis.
Norah G Verbout, Weiping Su, Peter Pham, Kelley Jordan, Tia Cl Kohs

Res Sq· April 2023

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The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial.
Christina U Lorentz, Erik I Tucker, Norah G Verbout, Joseph J Shatzel, Sven R Olson

Blood· December 2021

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Thrombin generation and activity in multiple sclerosis.
Kelley R Jordan, Ivan Parra-Izquierdo, András Gruber, Joseph J Shatzel, Peter Pham, Norah G Verbout

Metab Brain Dis· March 2021

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The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Erik I Tucker, Norah G Verbout, Brandon D Markway, Michael Wallisch, Christina U Lorentz

Blood· February 2020

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Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Christina U Lorentz, Norah G Verbout, Michael Wallisch, Matthew W Hagen, Joseph J Shatzel

Arterioscler Thromb Vasc Biol· April 2019

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Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Christina U Lorentz, Norah G Verbout, Zhiping Cao, Lijuan Liu, Monica T Hinds

Blood Adv· January 2018

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Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.
Norah G Verbout, Xiaolin Yu, Laura D Healy, Kevin G Phillips, Erik I Tucker

Metab Brain Dis· February 2015

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Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.
David I Kasahara, Hye Y Kim, Joel A Mathews, Norah G Verbout, Alison S Williams

Am J Physiol Lung Cell Mol Physiol· March 2014

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Impact of adiponectin overexpression on allergic airways responses in mice.
Norah G Verbout, Leandro Benedito, Alison S Williams, David I Kasahara, Allison P Wurmbrand

J Allergy (Cairo)· July 2013

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Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice.
Alison S Williams, David I Kasahara, Norah G Verbout, Alexey V Fedulov, Ming Zhu

PLoS One· January 2013

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Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
Philberta Y Leung, Sawan Hurst, Michelle A Berny-Lang, Norah G Verbout, David Gailani

Transl Stroke Res· September 2012

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Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Erik I Tucker, Norah G Verbout, Philberta Y Leung, Sawan Hurst, Owen J T McCarty

Blood· May 2012

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Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A.
David I Kasahara, Hye Y Kim, Alison S Williams, Norah G Verbout, Jennifer Tran

J Immunol· May 2012

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Muscarinic receptor agonists and antagonists: effects on inflammation and immunity.
Norah G Verbout, David B Jacoby

Handb Exp Pharmacol· April 2012

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Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes.
Asako Itakura, Norah G Verbout, Kevin G Phillips, Robert H Insall, David Gailani

J Leukoc Biol· November 2011

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Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Ming Zhu, Christopher Hug, David I Kasahara, Richard A Johnston, Alison S Williams, Norah G Verbout

Am J Respir Cell Mol Biol· October 2010

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Pulmonary responses to subacute ozone exposure in obese vs. lean mice.
Stephanie A Shore, Jason E Lang, David I Kasahara, Frank L Lu, Norah G Verbout

J Appl Physiol (1985)· November 2009

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Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor.
Norah G Verbout, David B Jacoby, Gerald J Gleich, Allison D Fryer

Am J Physiol Lung Cell Mol Physiol· August 2009

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Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects.
Liliana Moreno-Vinasco, Norah G Verbout, Allison D Fryer, David B Jacoby

Am J Physiol Lung Cell Mol Physiol· August 2009

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Atropine pretreatment enhances airway hyperreactivity in antigen-challenged guinea pigs through an eosinophil-dependent mechanism.
Norah G Verbout, Jesse K Lorton, David B Jacoby, Allison D Fryer

Am J Physiol Lung Cell Mol Physiol· May 2007

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