Publications by authors named "Noritaka Hashii"

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Versatile intact LC-MS method for evaluating the drug-antibody ratio and drug load distribution of antibody-drug conjugates in human plasma.
Noritaka Hashii, Yusuke Haruyama, Ryu Hirayama, Ryo Kajita, Yuki Kishino

J Chromatogr B Analyt Technol Biomed Life Sci· May 2025

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Multi-attribute method analysis of therapeutic monoclonal antibodies using an automated sample preparation system.
Noritaka Hashii, Chihiro Obata, Miho Okada, Shota Nakamura, Keisuke Fukazawa

J Pharm Biomed Anal· January 2025

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Designing strong inducible synthetic promoters in yeasts.
Masahiro Tominaga, Yoko Shima, Kenta Nozaki, Yoichiro Ito, Masataka Someda, Noritaka Hashii

Nat Commun· December 2024

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Involvement of Metalloproteases in the Fertilization of the Ascidian .
Hitoshi Sawada, Ikuya Hattori, Noritaka Hashii, Takako Saito

Biomolecules· November 2024

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Usefulness of Size-Exclusion Chromatography-Multi-Angle Light Scattering to Assess Particle Composition and Protein Impurities for Quality Control of Therapeutic Exosome Preparations.
Hirotaka Nishimura, Noritaka Hashii, Tomofumi Yamamoto, Yuchen Sun, Takumi Miura

Pharmaceutics· November 2024

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Pathogenicity of IgG-Fc desialylation and its association with Th17 cells in an animal model of systemic lupus erythematosus.
Yuri Nishida, Mirei Shirakashi, Noritaka Hashii, Ran Nakashima, Yoichi Nakayama

Mod Rheumatol· March 2024

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Intracellular polyamine depletion induces N-linked galactosylation of the monoclonal antibody produced by CHO DP-12 cells.
Rin Miyajima, Hitomi Manaka, Tatsuya Honda, Noritaka Hashii, Masato Suzuki

J Biotechnol· December 2023

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Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees.
Takeshi Inoue, Ryo Shinnakasu, Chie Kawai, Hiromi Yamamoto, Shuhei Sakakibara, Noritaka Hashii

J Exp Med· February 2023

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Development of a penetratin-conjugated stapled peptide that inhibits Wnt/β-catenin signaling.
Keisuke Tsuchiya, Masato Kiyoshi, Noritaka Hashii, Minami Fujita, Takashi Kurohara

Bioorg Med Chem· November 2022

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[Quality Evaluation of Therapeutic Antibodies by Multi-attribute Method].
Noritaka Hashii, Michiko Tajiri, Akiko Ishii-Watabe

Yakugaku Zasshi· July 2022

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The influence of antibody engineering on Fc conformation and Fc receptor binding properties: Analysis of FcRn-binding engineered antibodies and an Fc fusion protein.
Takuo Suzuki, Noritaka Hashii, Minoru Tada, Akiko Ishii-Watabe

MAbs· December 2021

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Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses.
Ryo Shinnakasu, Shuhei Sakakibara, Hiromi Yamamoto, Po-Hung Wang, Saya Moriyama, Noritaka Hashii

J Exp Med· December 2021

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Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD.
Ginto George, Satoshi Ninagawa, Hirokazu Yagi, Jun-Ichi Furukawa, Noritaka Hashii

Elife· October 2021

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Site-Specific O-Glycosylation Analysis by Liquid Chromatography-Mass Spectrometry with Electron-Transfer/Higher-Energy Collisional Dissociation.
Noritaka Hashii, Junya Suzuki

Methods Mol Biol· June 2021

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Glycosylation decreases aggregation and immunogenicity of adalimumab Fab secreted from Pichia pastoris.
Hitomi Nakamura, Masato Kiyoshi, Makoto Anraku, Noritaka Hashii, Naoko Oda-Ueda

J Biochem· April 2021

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Bioanalysis of therapeutic monoclonal antibody by peptide adsorption-controlled LC-MS.
Noritaka Hashii, Yoshiko Tousaka, Koji Arai, Yoshimasa Enoki, Suguru Fukuda

Bioanalysis· February 2021

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Establishment of a highly precise multi-attribute method for the characterization and quality control of therapeutic monoclonal antibodies.
Michiko Tajiri-Tsukada, Noritaka Hashii, Akiko Ishii-Watabe

Bioengineered· December 2020

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Generic MS-based method for the bioanalysis of therapeutic monoclonal antibodies in nonclinical studies.
Noritaka Hashii, Yoshiko Tousaka, Koji Arai, Ryoya Goda, Noriko Inoue

Bioanalysis· February 2020

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Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies.
Michihiko Aoyama, Noritaka Hashii, Wataru Tsukimura, Kenji Osumi, Akira Harazono

MAbs· July 2019

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Vitelline membrane proteins promote left-sided nodal expression after neurula rotation in the ascidian, Halocynthia roretzi.
Yuka Tanaka, Shiori Yamada, Samantha L Connop, Noritaka Hashii, Hitoshi Sawada

Dev Biol· May 2019

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In-depth site-specific O-Glycosylation analysis of therapeutic Fc-fusion protein by electron-transfer/higher-energy collisional dissociation mass spectrometry.
Noritaka Hashii, Junya Suzuki, Hisatoshi Hanamatsu, Jun-Ichi Furukawa, Akiko Ishii-Watabe

Biologicals· March 2019

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[Site-specific O-Glycosylation Analysis of Therapeutic Fc-fusion Protein by Mass Spectrometry].
Noritaka Hashii, Akiko Ishii-Watabe

Yakugaku Zasshi· February 2019

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Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).
Michihiko Aoyama, Minoru Tada, Ken-Ichiro Tatematsu, Noritaka Hashii, Hideki Sezutsu

Biochem Biophys Res Commun· September 2018

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Characteristic glycopeptides associated with extreme human longevity identified through plasma glycoproteomics.
Yuri Miura, Noritaka Hashii, Yuki Ohta, Yoko Itakura, Hiroki Tsumoto

Biochim Biophys Acta Gen Subj· June 2018

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Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column.
Masato Kiyoshi, Jose M M Caaveiro, Minoru Tada, Hiroko Tamura, Toru Tanaka, Noritaka Hashii

Sci Rep· March 2018

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