Publications by authors named "Nuala McCabe"

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ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation.
Conor Hanna, Victoria L Dunne, Steven M Walker, Karl T Butterworth, Nuala McCabe

Cancers (Basel)· December 2020

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miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA.
Jessica Ray, Charles Haughey, Christianne Hoey, Jouhyun Jeon, Ross Murphy, Nuala McCabe

Cancer Lett· March 2020

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Defining the molecular evolution of extrauterine high grade serous carcinoma.
James P Beirne, Darragh G McArt, Aideen Roddy, Clara McDermott, Jennifer Ferris, Nuala McCabe

Gynecol Oncol· November 2019

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DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy.
Elaine Gilmore, Nuala McCabe, Richard D Kennedy, Eileen E Parkes

J Oncol· June 2019

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A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer.
Richard D A Wilkinson, Roberta E Burden, Sara H McDowell, Darragh G McArt, Stephen McQuaid, Nuala McCabe

J Oncol· June 2019

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FES-related tyrosine kinase activates the insulin-like growth factor-1 receptor at sites of cell adhesion.
Joanna Stanicka, Leonie Rieger, Sandra O'Shea, Orla Cox, Michael Coleman, Nuala McCabe

Oncogene· June 2018

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Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer.
Niamh McGivern, Aya El-Helali, Paul Mullan, Iain A McNeish, D Paul Harkin, Nuala McCabe

Oncotarget· January 2018

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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.
Eileen E Parkes, Steven M Walker, Laura E Taggart, Nuala McCabe, Laura A Knight

J Natl Cancer Inst· January 2017

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Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line.
Jaine K Blayney, Timothy Davison, Nuala McCabe, Steven Walker, Karen Keating

Nucleic Acids Res· September 2016

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IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin.
Ciara H O'Flanagan, Sandra O'Shea, Amy Lyons, Fionola M Fogarty, Nuala McCabe

Oncotarget· August 2016

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The role of PTEN as a cancer biomarker.
Nuala McCabe, Richard D Kennedy, Kevin M Prise

Oncoscience· March 2016

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When the guardian becomes the enemy: Targeting ATM in PTEN-deficient cancers.
Nuala McCabe, Steven M Walker, Richard D Kennedy

Mol Cell Oncol· January 2016

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Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM.
Nuala McCabe, Conor Hanna, Steven M Walker, David Gonda, Jie Li

Cancer Res· June 2015

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Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma.
Pamela J Maxwell, Jonathan Coulter, Steven M Walker, Melanie McKechnie, Jessica Neisen, Nuala McCabe

Eur Urol· August 2013

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DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1.
Sarah A Martin, Nuala McCabe, Michelle Mullarkey, Robert Cummins, Darren J Burgess

Cancer Cell· March 2010

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Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition.
Nuala McCabe, Nicholas C Turner, Christopher J Lord, Katarzyna Kluzek, Aneta Bialkowska

Cancer Res· August 2006

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BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency.
Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Niall M B Martin, Graeme C M Smith

Cancer Biol Ther· September 2005

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson

Nature· April 2005

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BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3.
Paula M Gilmore, Nuala McCabe, Jennifer E Quinn, Richard D Kennedy, Julia J Gorski

Cancer Res· June 2004

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X-chromosome inactivation: X marks the spot for BRCA1.
Caroline Stone, Nuala McCabe, Alan Ashworth

Curr Biol· January 2003

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BRCA1 regulates the interferon gamma-mediated apoptotic response.
Heather N Andrews, Paul B Mullan, Stewart McWilliams, Sarka Sebelova, Jennifer E Quinn, Nuala McCabe

J Biol Chem· July 2002

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