Publications by authors named "Ofra Novoplansky"

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Dual inhibition of HERs and PD-1 counteract resistance in KRAS-mutant head and neck cancer.
Ofra Novoplansky, Sankar Jagadeeshan, Manu Prasad, Ksenia M Yegodayev, Divyasree Marripati

J Exp Clin Cancer Res· November 2024

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Activation of the EGFR/PI3K/AKT pathway limits the efficacy of trametinib treatment in head and neck cancer.
Ofra Novoplansky, Avital B Shnerb, Divyasree Marripati, Sankar Jagadeeshan, Raghda Abu Shareb

Mol Oncol· December 2023

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New insights into RAS in head and neck cancer.
Sankar Jagadeeshan, Ofra Z Novoplansky, Oded Cohen, Ina Kurth, Jochen Hess

Biochim Biophys Acta Rev Cancer· November 2023

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Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy.
Noam Tzuri, Ksenia M Yegodayev, Ofra Novoplansky, Moshe Elkabets, Amir Aharoni

Sci Rep· July 2023

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The Contribution of the Minimal Promoter Element to the Activity of Synthetic Promoters Mediating CAR Expression in the Tumor Microenvironment.
Yariv Greenshpan, Omri Sharabi, Ksenia M Yegodayev, Ofra Novoplansky, Moshe Elkabets

Int J Mol Sci· July 2022

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Worldwide Prevalence and Clinical Characteristics of RAS Mutations in Head and Neck Cancer: A Systematic Review and Meta-Analysis.
Ofra Novoplansky, Sankar Jagadeeshan, Ohad Regev, Idan Menashe, Moshe Elkabets

Front Oncol· May 2022

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MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer.
Manu Prasad, Jonathan Zorea, Sankar Jagadeeshan, Avital B Shnerb, Sooraj Mathukkada, Ofra Novoplansky

J Immunother Cancer· March 2022

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Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs.
Divya Ram Jayaram, Sigal Frost, Chanan Argov, Vijayasteltar Belsamma Liju, Nikhil Ponnoor Anto, Ofra Novoplansky

Proc Natl Acad Sci U S A· October 2021

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EGFR overexpression increases radiotherapy response in HPV-positive head and neck cancer through inhibition of DNA damage repair and HPV E6 downregulation.
Elham Nafea Alsahafi, Selvam Thavaraj, Nazanin Sarvestani, Ofra Novoplansky, Moshe Elkabets

Cancer Lett· February 2021

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TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors.
Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M Schram, Helen H Won, Ofra Novoplansky

Cancer Discov· January 2021

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TGF-Beta-Activated Cancer-Associated Fibroblasts Limit Cetuximab Efficacy in Preclinical Models of Head and Neck Cancer.
Ksenia M Yegodayev, Ofra Novoplansky, Artemiy Golden, Manu Prasad, Liron Levin

Cancers (Basel)· February 2020

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MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer.
Ofra Novoplansky, Matthew Fury, Manu Prasad, Ksenia Yegodayev, Jonathan Zorea

Int J Cancer· August 2019

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Ubiquitin Accumulation on Disease Associated Protein Aggregates Is Correlated with Nuclear Ubiquitin Depletion, Histone De-Ubiquitination and Impaired DNA Damage Response.
Adi Ben Yehuda, Marwa Risheq, Ofra Novoplansky, Kirill Bersuker, Ron R Kopito

PLoS One· August 2017

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