Publications by authors named "Ofra Sabag"

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Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity.
Ahmed Radwan, Jason Eccleston, Ofra Sabag, Howard Marcus, Jonathan Sussman

Proc Natl Acad Sci U S A· September 2024

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Hepatocyte regeneration is driven by embryo-like DNA methylation reprogramming.
Tal Falick Michaeli, Ofra Sabag, Batia Azria, Rimma Fok, Nathalie Abudi

Proc Natl Acad Sci U S A· April 2024

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Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects.
Rachel Lasry, Noam Maoz, Albert W Cheng, Nataly Yom Tov, Elisabeth Kulenkampff, Ofra Sabag

Stem Cell Reports· November 2023

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Pluripotency-independent induction of human trophoblast stem cells from fibroblasts.
Moriyah Naama, Moran Rahamim, Valery Zayat, Shulamit Sebban, Ahmed Radwan, Ofra Sabag

Nat Commun· June 2023

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Laminin111-based defined culture promoting self-renewing human pluripotent stem cells with properties of the early post-implantation epiblast.
Michal Gropp, Ithai Waldhorn, Yaniv Gil, Debora Steiner, Tikva Tako Turetsky, Ofra Sabag

Stem Cell Reports· December 2022

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Muscle injury causes long-term changes in stem-cell DNA methylation.
Tal Falick Michaeli, Ofra Sabag, Rimma Fok, Batia Azria, Jonathan Monin

Proc Natl Acad Sci U S A· December 2022

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The role of DNA methylation in genome-wide gene regulation during development.
Howard Cedar, Ofra Sabag, Yitzhak Reizel

Development· January 2022

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Determining gestational age using genome methylation profile: A novel approach for fetal medicine.
Tal Falick Michaeli, Adam Spiro, Ofra Sabag, Gilad Karavani, Simha Yagel

Prenat Diagn· October 2019

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Role of transcription complexes in the formation of the basal methylation pattern in early development.
Razi Greenfield, Amalia Tabib, Ilana Keshet, Joshua Moss, Ofra Sabag

Proc Natl Acad Sci U S A· October 2018

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Postnatal DNA demethylation and its role in tissue maturation.
Yitzhak Reizel, Ofra Sabag, Yael Skversky, Adam Spiro, Benjamin Steinberg

Nat Commun· May 2018

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Gender-specific postnatal demethylation and establishment of epigenetic memory.
Yitzhak Reizel, Adam Spiro, Ofra Sabag, Yael Skversky, Merav Hecht

Genes Dev· May 2015

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Combining flagellin and human β-defensin-3 to combat bacterial infections.
Ofra Sabag, Haya Lorberboum-Galski

Front Microbiol· December 2014

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Establishment of methylation patterns in ES cells.
Ofra Sabag, Ayelet Zamir, Ilana Keshet, Merav Hecht, Guy Ludwig

Nat Struct Mol Biol· January 2014

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Soluble CD40 ligand (sCD40L) provides a new delivery system for targeted treatment: sCD40L-caspase 3 chimeric protein for treating B-cell malignancies.
Rotem Kedar, Ofra Sabag, Michal Licthenstein, Haya Lorberboum-Galski

Cancer· December 2012

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Eliminating the six N-terminal amino acids of the caspase 3 large subunit improved production of a biologically active IL2-Caspase3 chimeric protein.
Yitav Glantz, Ofra Sabag, Michal Lichtenstein, Inna Grodzovski, Haya Lorberboum-Galski

Biotechnol Prog· July 2012

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α-Synuclein expression selectively affects tumorigenesis in mice modeling Parkinson's disease.
Eitan Israeli, Eugenia Yakunin, Yonaton Zarbiv, Amir Hacohen-Solovich, Haya Kisos, Ofra Sabag

PLoS One· September 2011

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Successful TAT-mediated enzyme replacement therapy in a mouse model of mitochondrial E3 deficiency.
Matan Rapoport, Lina Salman, Ofra Sabag, Mulchand S Patel, Haya Lorberboum-Galski

J Mol Med (Berl)· February 2011

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Utilizing a GnRH-based chimeric protein for the detection of adenocarcinoma.
Michal Lichtenstein, Ahmi Ben-Yehudah, Ruth Belostotsky, Ronen Eaveri, Ofra Sabag

Int J Oncol· July 2005

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