Publications by authors named "Ofra Yanuka"

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Genome-Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours.
Rivki Cashman, Guy Haim-Abadi, Elyad Lezmi, Hagit Philip, Jonathan Nissenbaum, Ofra Yanuka

Cell Prolif· November 2025

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Predicting tumour resistance to paclitaxel and carboplatin utilising genome-wide screening in haploid human embryonic stem cells.
Jonathan Nissenbaum, Emanuel Segal, Hagit Philip, Rivki Cashman, Tamar Golan-Lev, Ofra Yanuka

Cell Prolif· March 2025

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Genome-wide screening reveals essential roles for HOX genes and imprinted genes during caudal neurogenesis of human embryonic stem cells.
Shay Kinreich, Anna Bialer-Tsypin, Ruth Viner-Breuer, Gal Keshet, Roni Suhler, Ofra Yanuka

Stem Cell Reports· November 2024

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Differentiation of uniparental human embryonic stem cells into granulosa cells reveals a paternal contribution to gonadal development.
Gal Keshet, Shiran Bar, Roni Sarel-Gallily, Ofra Yanuka, Nissim Benvenisty

Stem Cell Reports· April 2023

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Genome-wide screening for genes involved in the epigenetic basis of fragile X syndrome.
Dan Vershkov, Atilgan Yilmaz, Ofra Yanuka, Anders Lade Nielsen, Nissim Benvenisty

Stem Cell Reports· May 2022

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Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells.
Shiran Bar, Dan Vershkov, Gal Keshet, Elyad Lezmi, Naama Meller, Ofra Yanuka

Nat Commun· November 2021

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Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells.
Ido Sagi, Joao C De Pinho, Michael V Zuccaro, Chen Atzmon, Tamar Golan-Lev, Ofra Yanuka

Cell Stem Cell· September 2019

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Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells.
Uri Weissbein, Mordecai Peretz, Omer Plotnik, Ofra Yanuka, Ido Sagi

iScience· January 2019

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Epigenetic mechanism of FMR1 inactivation in Fragile X syndrome.
Merav Hecht, Amalia Tabib, Tamar Kahan, Shari Orlanski, Michal Gropp, Ofra Yanuka

Int J Dev Biol· June 2018

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Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation.
Tomer Halevy, Juan-Carlos Biancotti, Ofra Yanuka, Tamar Golan-Lev, Nissim Benvenisty

Stem Cell Reports· October 2016

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Derivation and differentiation of haploid human embryonic stem cells.
Ido Sagi, Gloryn Chia, Tamar Golan-Lev, Mordecai Peretz, Uri Weissbein, Ofra Yanuka

Nature· April 2016

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Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons.
Chul-Yong Park, Tomer Halevy, Dongjin R Lee, Jin Jea Sung, Jae Souk Lee, Ofra Yanuka

Cell Rep· October 2015

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Aberrant DNA methylation in ES cells.
Guy Ludwig, Deborah Nejman, Merav Hecht, Shari Orlanski, Monther Abu-Remaileh, Ofra Yanuka

PLoS One· June 2015

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The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome.
Yonatan Stelzer, Ido Sagi, Ofra Yanuka, Rachel Eiges, Nissim Benvenisty

Nat Genet· June 2014

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Human pluripotent stem cells with distinct X inactivation status show molecular and cellular differences controlled by the X-Linked ELK-1 gene.
Tal Bruck, Ofra Yanuka, Nissim Benvenisty

Cell Rep· July 2013

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Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen.
Uri Ben-David, Qing-Fen Gan, Tamar Golan-Lev, Payal Arora, Ofra Yanuka

Cell Stem Cell· February 2013

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Reprogramming of the MHC-I and its regulation by NFκB in human-induced pluripotent stem cells.
Marjorie Pick, Daniel Ronen, Ofra Yanuka, Nissim Benvenisty

Stem Cells· December 2012

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Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells.
Yoav Mayshar, Ofra Yanuka, Nissim Benvenisty

J Cell Mol Med· June 2011

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Global analysis of parental imprinting in human parthenogenetic induced pluripotent stem cells.
Yonatan Stelzer, Ofra Yanuka, Nissim Benvenisty

Nat Struct Mol Biol· June 2011

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Human embryonic stem cells as models for aneuploid chromosomal syndromes.
Juan-Carlos Biancotti, Kavita Narwani, Nicole Buehler, Berhan Mandefro, Tamar Golan-Lev, Ofra Yanuka

Stem Cells· September 2010

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Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos.
Rachel Eiges, Achia Urbach, Mira Malcov, Tsvia Frumkin, Tamar Schwartz, Ofra Yanuka

Cell Stem Cell· November 2007

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Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.
Tamar Dvash, Nadav Sharon, Ofra Yanuka, Nissim Benvenisty

Stem Cells· February 2007

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The effect of overexpression of Pdx1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells.
Neta Lavon, Ofra Yanuka, Nissim Benvenisty

Stem Cells· August 2006

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Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies.
Tamar Dvash, Yoav Mayshar, Henia Darr, Michael McElhaney, Douglas Barker, Ofra Yanuka

Hum Reprod· December 2004

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Differentiation and isolation of hepatic-like cells from human embryonic stem cells.
Neta Lavon, Ofra Yanuka, Nissim Benvenisty

Differentiation· June 2004

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