Publications by authors named "Olaf R Mook"

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Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects.
Terry Vrijenhoek, Ken Kraaijeveld, Martin Elferink, Joep de Ligt, Elcke Kranendonk, Olaf R Mook

Eur J Hum Genet· September 2015

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Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects.
Terry Vrijenhoek, Ken Kraaijeveld, Martin Elferink, Joep de Ligt, Elcke Kranendonk, Olaf R Mook

Eur J Hum Genet· September 2015

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RELN rare variants in myoclonus-dystonia.
Justus L Groen, Katja Ritz, Hamid Jalalzadeh, Sandra M A van der Salm, Aldo Jongejan, Olaf R Mook

Mov Disord· March 2015

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Hennekam syndrome can be caused by FAT4 mutations and be allelic to Van Maldergem syndrome.
Mariëlle Alders, Lihadh Al-Gazali, Isabelle Cordeiro, Bruno Dallapiccola, Livia Garavelli, Olaf R Mook

Hum Genet· September 2014

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Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics.
Olaf R F Mook, Martin A Haagmans, Jean-François Soucy, Judith B A van de Meerakker, Frank Baas

J Med Genet· September 2013

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A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding.
Judith B A van de Meerakker, Imke Christiaans, Phil Barnett, Ronald H Lekanne Deprez, Aho Ilgun, Olaf R F Mook

Biochim Biophys Acta· April 2013

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Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo.
Maria B Laursen, Malgorzata M Pakula, Shan Gao, Kees Fluiter, Olaf R Mook

Mol Biosyst· May 2010

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Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.
Kees Fluiter, Olaf R F Mook, Jeroen Vreijling, Niels Langkjaer, Torben Højland

Mol Biosyst· August 2009

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Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes.
Agata Drewniak, Bram J van Raam, Judy Geissler, Anton T J Tool, Olaf R F Mook

Blood· June 2009

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The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence.
Kees Fluiter, Olaf R F Mook, Frank Baas

Methods Mol Biol· April 2009

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Noninvasive magnetic resonance imaging of the development of individual colon cancer tumors in rat liver.
Olaf R F Mook, Ard Jonker, Aart C Strang, Andor Veltien, Giulio Gambarota

Biotechniques· April 2008

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Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo.
Olaf R Mook, Frank Baas, Marit B de Wissel, Kees Fluiter

Mol Cancer Ther· March 2007

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The role of gelatinases in colorectal cancer progression and metastasis.
Olaf R F Mook, Wilma M Frederiks, Cornelis J F Van Noorden

Biochim Biophys Acta· December 2004

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Metabolic mapping of proteinase activity with emphasis on in situ zymography of gelatinases: review and protocols.
Wilma M Frederiks, Olaf R F Mook

J Histochem Cytochem· June 2004

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Visualization of early events in tumor formation of eGFP-transfected rat colon cancer cells in liver.
Olaf R F Mook, Jan Van Marle, Heleen Vreeling-Sindelárová, Remmet Jonges, Wilma M Frederiks

Hepatology· August 2003

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In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Olaf R F Mook, Claudia Van Overbeek, Eleonora G Ackema, Febe Van Maldegem, Wilma M Frederiks

J Histochem Cytochem· June 2003

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