Publications by authors named "Olaf Schaefer"

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Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban.
Yuri Tsuruya, Takeo Nakanishi, Hisakazu Komori, Xinying Wang, Naoki Ishiguro, Olaf Schaefer

J Pharm Sci· September 2017

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Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayers.
Naoki Ishiguro, Wataru Kishimoto, Astrid Volz, Eva Ludwig-Schwellinger, Thomas Ebner, Olaf Schaefer

Drug Metab Dispos· February 2014

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In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
Wataru Kishimoto, Naoki Ishiguro, Eva Ludwig-Schwellinger, Thomas Ebner, Olaf Schaefer

Drug Metab Dispos· February 2014

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Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner, Olaf Schaefer

Drug Metab Dispos· January 2013

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Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes.
Olaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner

Drug Metab Dispos· January 2012

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Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities.
Sumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner

Drug Metab Dispos· January 2012

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Reliability and robustness of simultaneous absolute quantification of drug transporters, cytochrome P450 enzymes, and Udp-glucuronosyltransferases in human liver tissue by multiplexed MRM/selected reaction monitoring mode tandem mass spectrometry with nano-liquid chromatography.
Atsushi Sakamoto, Takehisa Matsumaru, Naoki Ishiguro, Olaf Schaefer, Sumio Ohtsuki

J Pharm Sci· September 2011

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Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus.
Michael Hümpel, Päivi Isaksson, Olaf Schaefer, Ulrike Kaufmann, Paolo Ciana

J Steroid Biochem Mol Biol· November 2005

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Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices.
Olaf Schaefer, Rolf Bohlmann, Wolf-Dieter Schleuning, Kai Schulze-Forster, Michael Hümpel

J Agric Food Chem· April 2005

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Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.
Minghao Zhong, Melissa A Henriksen, Kenji Takeuchi, Olaf Schaefer, Bin Liu

Proc Natl Acad Sci U S A· March 2005

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8-Prenyl naringenin is a potent ERalpha selective phytoestrogen present in hops and beer.
Olaf Schaefer, Michael Hümpel, Karl-Heinrich Fritzemeier, Rolf Bohlmann, Wolf-Dieter Schleuning

J Steroid Biochem Mol Biol· February 2003

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Dissociation time from DNA determines transcriptional function in a STAT1 linker mutant.
Edward Yang, Melissa A Henriksen, Olaf Schaefer, Natalia Zakharova, James E Darnell

J Biol Chem· April 2002

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