Publications by authors named "Onno Roovers"

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Germline LCP1 mutations cause immunodeficiency with neutropenia, monocytopenia, lymphopenia and defective cytokinesis.
Thijs van Bergen, Dennis Bosch, Christine Bellanné-Chantelot, Roger Mulet-Lazaro, Jacob R Bledsoe, Onno Roovers

Blood Adv· October 2025

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Truncated CSF3 receptors induce pro-inflammatory responses in severe congenital neutropenia.
Patricia A Olofsen, Dennis A Bosch, Hans W J de Looper, Paulina M H van Strien, Remco M Hoogenboezem, Onno Roovers

Br J Haematol· January 2023

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PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations.
Patricia A Olofsen, Dennis A Bosch, Onno Roovers, Paulina M H van Strien, Hans W J de Looper

Blood Adv· February 2021

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Malignant Transformation Involving Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia.
Patricia A Olofsen, Szabolcs Fatrai, Paulina M H van Strien, Julia C Obenauer, Hans W J de Looper, Onno Roovers

Cell Rep Med· August 2020

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Lentiviral Hematopoietic Stem Cell Gene Therapy Corrects Murine Pompe Disease.
Merel Stok, Helen de Boer, Marshall W Huston, Edwin H Jacobs, Onno Roovers

Mol Ther Methods Clin Dev· June 2020

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Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia.
Roel Polak, Marc B Bierings, Cindy S van der Leije, Mathijs A Sanders, Onno Roovers

Haematologica· April 2019

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Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface.
Karishma Palande, Onno Roovers, Judith Gits, Carola Verwijmeren, Yoshihito Iuchi

J Cell Sci· November 2011

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The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
Annemarie Meenhuis, Carola Verwijmeren, Onno Roovers, Ivo P Touw

Biochem J· March 2011

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Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor.
Albert Wölfler, Mahban Irandoust, Annemarie Meenhuis, Judith Gits, Onno Roovers

Traffic· August 2009

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Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors.
Annemarie Meenhuis, Mahban Irandoust, Albert Wölfler, Onno Roovers, Marijke Valkhof

Biochem J· February 2009

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Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor.
Mahban I Irandoust, Lambertus H J Aarts, Onno Roovers, Judith Gits, Stefan J Erkeland

EMBO J· April 2007

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Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics.
Lambertus H J Aarts, Onno Roovers, Alister C Ward, Ivo P Touw

Blood· January 2004

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