Publications by authors named "Orie Tajima"

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GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics.
Koichi Furukawa, Yuhsuke Ohmi, Kazunori Hamamura, Yuki Ohkawa, Noboru Hashimoto, Orie Tajima

Cancer Sci· April 2025

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Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins.
Mohammad Abul Hasnat, Yuhsuke Ohmi, Farhana Yesmin, Kei Kaneko, Mariko Kambe, Orie Tajima

Int J Mol Sci· November 2024

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Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells.
Mohammad Abul Hasnat, Yuhsuke Ohmi, Farhana Yesmin, Mariko Kambe, Yoshiyuki Kawamoto, Orie Tajima

Nagoya J Med Sci· August 2024

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Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene.
Koichi Furukawa, Kogo Takamiya, Yuhsuke Ohmi, Robiul H Bhuiyan, Orie Tajima

FEBS Open Bio· September 2023

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Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas.
Farhana Yesmin, Keiko Furukawa, Mariko Kambe, Yuhsuke Ohmi, Robiul Hasan Bhuiyan, Orie Tajima

Sci Rep· March 2023

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Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway.
Orie Tajima, Yuki Fujita, Yuhsuke Ohmi, Koichi Furukawa, Keiko Furukawa

PLoS One· February 2023

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Signaling domains of cancer-associated glycolipids.
Koichi Furukawa, Yuhsuke Ohmi, Kazunori Hamamura, Yuji Kondo, Yuki Ohkawa, Orie Tajima

Glycoconj J· April 2022

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Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins.
Farhana Yesmin, Robiul H Bhuiyan, Yuhsuke Ohmi, Satoko Yamamoto, Kei Kaneko, Orie Tajima

Int J Mol Sci· December 2021

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Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia.
Farhana Yesmin, Robiul H Bhuiyan, Yuhsuke Ohmi, Yuki Ohkawa, Orie Tajima

J Biochem· August 2020

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Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering.
Koichi Furukawa, Yuhsuke Ohmi, Farhana Yesmin, Orie Tajima, Yuji Kondo

Int J Mol Sci· March 2020

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TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes.
Rika Takeuchi, Mariko Kambe, Maiko Miyata, Upul Jeyadevan, Orie Tajima

Sci Rep· October 2019

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New era of research on cancer-associated glycosphingolipids.
Koichi Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Robiul H Bhuiyan, Pu Zhang, Orie Tajima

Cancer Sci· May 2019

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Differential roles of gangliosides in malignant properties of melanomas.
Yuhsuke Ohmi, Mariko Kambe, Yuki Ohkawa, Kazunori Hamamura, Orie Tajima

PLoS One· April 2019

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Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration - Great progress over the last 70 years.
Koichi Furukawa, Yuhsuke Ohmi, Yuji Kondo, Robiul H Bhuiyan, Orie Tajima

Proc Jpn Acad Ser B Phys Biol Sci· April 2019

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Gangliosides in Inflammation and Neurodegeneration.
Koichi Furukawa, Yuhsuke Ohmi, Orie Tajima, Yuki Ohkawa, Yuji Kondo

Prog Mol Biol Transl Sci· February 2019

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Glycolipids: Essential regulator of neuro-inflammation, metabolism and gliomagenesis.
Koichi Furukawa, Yuhsuke Ohmi, Shuting Ji, Pu Zhang, Robiul H Bhuiyan, Orie Tajima

Biochim Biophys Acta Gen Subj· October 2017

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Regulatory function of glycosphingolipids in the inflammation and degeneration.
Koichi Furukawa, Yuhsuke Ohmi, Yuji Kondo, Yuki Ohkawa, Orie Tajima

Arch Biochem Biophys· April 2015

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UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.
Maiko Miyata, Masatoshi Ichihara, Orie Tajima, Sayaka Sobue, Mariko Kambe

Biochem Biophys Res Commun· March 2014

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Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord.
Yuhsuke Ohmi, Yuki Ohkawa, Orie Tajima, Yasuo Sugiura, Keiko Furukawa

J Neuroinflammation· March 2014

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Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas.
Keiko Furukawa, Mariko Kambe, Maiko Miyata, Yuki Ohkawa, Orie Tajima

Cancer Sci· January 2014

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Glycosphingolipids in the regulation of the nervous system.
Koichi Furukawa, Yusuke Ohmi, Yuki Ohkawa, Orie Tajima, Keiko Furukawa

Adv Neurobiol· January 2014

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Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.
Yuhsuke Ohmi, Yuki Ohkawa, Yoshio Yamauchi, Orie Tajima, Keiko Furukawa

Neurochem Res· June 2012

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Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.
Maiko Miyata, Mariko Kambe, Orie Tajima, Setsuko Moriya, Hiromichi Sawaki

Cancer Sci· December 2011

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Regulatory mechanisms of nervous systems with glycosphingolipids.
Koichi Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Noriyo Tokuda, Yuji Kondo, Orie Tajima

Neurochem Res· September 2011

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Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling.
Yuki Ohkawa, Yuhsuke Ohmi, Orie Tajima, Yoshio Yamauchi, Keiko Furukawa

Biochem Biophys Res Commun· August 2011

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