Publications by authors named "Orla Deevy"

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Dominant-negative effects of Weaver syndrome-associated EZH2 variants.
Orla Deevy, Jingjing Li, Craig Monger, Francesca Matrà, Ellen Tuck

Genes Dev· November 2025

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A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.
Rachel McCole, James Nolan, David M Reck, Craig Monger, Samantha Rustichelli, Orla Deevy

Cell Rep· January 2025

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Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.
Gerard L Brien, Raul Bardini Bressan, Craig Monger, Dáire Gannon, Eimear Lagan, Orla Deevy

Nat Genet· August 2021

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ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.
Zulekha A Qadeer, David Valle-Garcia, Dan Hasson, Zhen Sun, April Cook, Orla Deevy

Cancer Cell· November 2019

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PRC2 functions in development and congenital disorders.
Orla Deevy, Adrian P Bracken

Development· October 2019

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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Eric Conway, Emilia Jerman, Evan Healy, Shinsuke Ito, Daniel Holoch, Orla Deevy

Mol Cell· May 2018

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