Publications by authors named "Orla Finucane"

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Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction.
Jessica C Ralston, Marie-Sophie Nguyen-Tu, Claire L Lyons, Aoife A Cooke, Aoife M Murphy, Orla M Finucane

Br J Nutr· August 2020

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The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages.
Orla M Finucane, Jamie Sugrue, Ana Rubio-Araiz, Marie-Victoire Guillot-Sestier, Marina A Lynch

Sci Rep· March 2019

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Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid.
Ana Rubio-Araiz, Orla M Finucane, Samuel Keogh, Marina A Lynch

J Neuroinflammation· August 2018

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FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation.
Róisín M McManus, Orla M Finucane, Mieszko M Wilk, Kingston H G Mills, Marina A Lynch

J Neuroimmune Pharmacol· December 2017

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A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome-mediated inflammation and improving insulin signaling.
Niamh P Healy, Anna M Kirwan, Maeve A McArdle, Kieran Holohan, Alice B Nongonierma, Orla M Finucane

Mol Nutr Food Res· November 2016

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High-Density Lipoprotein Proteomic Composition, and not Efflux Capacity, Reflects Differential Modulation of Reverse Cholesterol Transport by Saturated and Monounsaturated Fat Diets.
Marcella O'Reilly, Eugene Dillon, Weili Guo, Orla Finucane, Aoibheann McMorrow

Circulation· May 2016

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Macrophage migration inhibitory factor deficiency ameliorates high-fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic steatosis.
Orla M Finucane, Clare M Reynolds, Fiona C McGillicuddy, Karen A Harford, Martine Morrison

PLoS One· January 2016

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Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.
Orla M Finucane, Claire L Lyons, Aoife M Murphy, Clare M Reynolds, Rut Klinger

Diabetes· June 2015

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Interactions between differential fatty acids and inflammatory stressors-impact on metabolic health.
Aoife M Murphy, Claire L Lyons, Orla M Finucane, Helen M Roche

Prostaglandins Leukot Essent Fatty Acids· January 2015

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Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.
Fiona C McGillicuddy, Clare M Reynolds, Orla Finucane, Eilish Coleman, Karen A Harford

Am J Physiol Endocrinol Metab· October 2013

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Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies.
Maeve A McArdle, Orla M Finucane, Ruth M Connaughton, Aoibheann M McMorrow, Helen M Roche

Front Endocrinol (Lausanne)· May 2013

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Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance.
Orla M Finucane, Clare M Reynolds, Fiona C McGillicuddy, Helen M Roche

Proc Nutr Soc· November 2012

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Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance.
Clare M Reynolds, Fiona C McGillicuddy, Karen A Harford, Orla M Finucane, Kingston H G Mills

Mol Nutr Food Res· August 2012

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