Publications by authors named "Orna Levran"

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Predictors of treatment retention and survival among methadone-maintained patients: A possible role for a functional delta opioid receptor gene variant.
Einat Peles, Yuli Kim, Anat Sason, Miriam Adelson, Orna Levran

Drug Alcohol Depend· September 2023

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Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
Nathan Gaddis, Ravi Mathur, Jesse Marks, Linran Zhou, Bryan Quach, Orna Levran

Sci Rep· October 2022

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Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder.
Einat Peles, Orna Levran, Matthew Randesi, Jurg Ott, Mary Jeanne Kreek

Eur Addict Res· September 2021

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Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis.
Orna Levran, Mary Jeanne Kreek

Mol Psychiatry· July 2021

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OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics.
Orna Levran, Matthew Randesi, Miriam Adelson, Mary Jeanne Kreek

Transl Psychiatry· May 2021

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Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians.
Matthew Randesi, John Rotrosen, Edward V Nunes, Joshua D Lee, Patricia Novo, Orna Levran

Am J Drug Alcohol Abuse· November 2020

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Further evidence for the association of ,  and  variants with opioid dependence.
Matthew Randesi, Orna Levran, Wim van den Brink, Peter Blanken, Jan M van Ree

Pharmacogenomics· August 2020

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Genetic Variant in the CRH-binding Protein Gene (CRHBP) is Associated With Cessation of Cocaine Use in Methadone Maintenance Patients With Opioid Addiction.
Einat Peles, Orna Levran, Matthew Randesi, Jurg Ott, Mary Jeanne Kreek

J Addict Med· July 2020

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A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction.
Orna Levran, Matthew Randesi, John Rotrosen, Jurg Ott, Miriam Adelson

PLoS One· April 2020

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A hominid-specific shift in cerebellar expression, upstream retrotransposons, and a potential cis-regulatory mechanism: bioinformatics analyses of the mu-opioid receptor gene.
Orna Levran, Eran Even-Tov, Li Zhao

Heredity (Edinb)· February 2020

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Extreme sampling design in genetic association mapping of quantitative trait loci using balanced and unbalanced case-control samples.
Yi Li, Orna Levran, JongJoo Kim, Tiejun Zhang, Xingdong Chen

Sci Rep· October 2019

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VMAT2 gene () variants associated with a greater risk for developing opioid dependence.
Matthew Randesi, Wim van den Brink, Orna Levran, Peter Blanken, Jan M van Ree

Pharmacogenomics· April 2019

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A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.
Orna Levran, Joel Correa da Rosa, Matthew Randesi, John Rotrosen, Miriam Adelson

PLoS One· December 2018

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Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features.
Eduardo R Butelman, Carina Y Chen, Rebecca S Fry, Rachel Kimani, Orna Levran

Drug Alcohol Depend· September 2018

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Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin.
Orna Levran, Einat Peles, Matthew Randesi, Joel Correa da Rosa, Pei-Hong Shen

Pharmacogenomics· March 2018

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Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls.
Matthew Randesi, Wim van den Brink, Orna Levran, Vadim Yuferov, Peter Blanken

Pharmacogenomics· January 2018

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The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment.
Orna Levran, Einat Peles, Matthew Randesi, Joel Correa da Rosa, Miriam Adelson

Pharmacogenomics· October 2017

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Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study.
Yong Zhang, Yupu Liang, Orna Levran, Matthew Randesi, Vadim Yuferov

Psychopharmacology (Berl)· August 2017

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Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury.
Matthew Randesi, Orna Levran, Joel Correa da Rosa, Julia Hankins, Jody Rule

Cell Mol Gastroenterol Hepatol· May 2017

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Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.
Matthew Randesi, Wim van den Brink, Orna Levran, Peter Blanken, Eduardo R Butelman

Drug Alcohol Depend· November 2016

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Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry.
Orna Levran, Einat Peles, Matthew Randesi, Joel Correa da Rosa, Jurg Ott

Pharmacogenomics· June 2016

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African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction.
Orna Levran, Matthew Randesi, Einat Peles, Joel Correa da Rosa, Jurg Ott

Pharmacogenomics· June 2016

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Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.
Tae-Hwi Schwantes-An, Juan Zhang, Li-Shiun Chen, Sarah M Hartz, Robert C Culverhouse, Orna Levran

Behav Genet· March 2016

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Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry.
Orna Levran, Einat Peles, Matthew Randesi, Joel Correa da Rosa, Jurg Ott

Prog Neuropsychopharmacol Biol Psychiatry· January 2016

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Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry.
Orna Levran, Einat Peles, Matthew Randesi, Joel Correa da Rosa, Jurg Ott

CNS Neurosci Ther· November 2015

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