Publications by authors named "P J Conn"

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Discovery of VU6052254: A Novel, Potent M Positive Allosteric Modulator.
Julie L Engers, Joseph D Bungard, Christopher C Presley, Irene Zagol-Ikapitte, Katherine J Watson, P Jeffrey Conn

ACS Chem Neurosci· December 2025

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Muscarinic Acetylcholine Receptor Activators as Transformative Therapeutics for Schizophrenia.
P Jeffrey Conn, Steven M Paul

Annu Rev Med· October 2025

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Safety, tolerability, pharmacokinetic and pharmacodynamic effects of the muscarinic M positive allosteric modulator VU0467319 for Alzheimer's disease: a single ascending-dose study in healthy participants.
Alexander C Conley, Alexandra P Key, Jennifer U Blackford, Jason K Russell, Kimberly M Albert, P Jeffrey Conn

Alzheimers Res Ther· July 2025

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Discovery of a Novel sp‑Rich M Positive Allosteric Modulators (PAMs) Chemotype via Scaffold Hopping.
Joseph D Bungard, Paul Spearing, Yu Nishio, Upendra Rathnayake, Chris C Presley, P Jeffrey Conn

ACS Med Chem Lett· July 2025

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Discovery of Pre-Clinical Candidate /: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy.
Julie L Engers, Sean R Bollinger, Alison R Gregro, Rory A Capstick, Paul K Spearing, P Jeffrey Conn

ACS Chem Neurosci· June 2025

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