Publications by authors named "P R Butchers"

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Discovery of a rapidly metabolized, long-acting β(2) adrenergic receptor agonist with a short onset time incorporating a sulfone group suitable for once-daily dosing.
Panayiotis A Procopiou, Victoria J Barrett, Keith Biggadike, Peter R Butchers, Andrew Craven

J Med Chem· January 2014

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The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating hydantoin or uracil rings.
Panayiotis A Procopiou, Victoria J Barrett, Nicola J Bevan, Peter R Butchers, Richard Conroy

Bioorg Med Chem· July 2011

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Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating metabolic inactivation: an antedrug approach.
Panayiotis A Procopiou, Victoria J Barrett, Nicola J Bevan, Keith Biggadike, Philip C Box, Peter R Butchers

J Med Chem· June 2010

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Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.
Panayiotis A Procopiou, Victoria J Barrett, Nicola J Bevan, Keith Biggadike, Peter R Butchers

J Med Chem· April 2009

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Pharmacological characterisation and inhibitory effects of (2R,3R,4S,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol, a novel ligand that demonstrates both adenosine A(2A) receptor agonist and adenosine A(3) receptor antagonist activity.
Nicola Bevan, Peter R Butchers, Rick Cousins, Jill Coates, Emma V Edgar

Eur J Pharmacol· June 2007

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