Publications by authors named "P Verhoest"

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Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.
Jamison B Tuttle, Christophe Allais, Charlotte M N Allerton, Annaliesa S Anderson, Joel T Arcari, Patrick R Verhoest

J Med Chem· April 2025

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A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19.
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Patrick R Verhoest

J Med Chem· August 2024

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Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.
Martin Pettersson, Douglas S Johnson, John M Humphrey, Christopher W Am Ende, Todd W Butler, Patrick R Verhoest

J Med Chem· June 2024

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Designing small molecules for therapeutic success: A contemporary perspective.
Tristan S Maurer, Martin Edwards, David Hepworth, Patrick Verhoest, Charlotte M N Allerton

Drug Discov Today· February 2022

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