Publications by authors named "Packianathan Charles"

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Structural basis for lipid and copper regulation of the ABC transporter MsbA.
Jixing Lyu, Chang Liu, Tianqi Zhang, Samantha Schrecke, Nicklaus P Elam, Charles Packianathan

Nat Commun· November 2022

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Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist.
Rui-Liang Lyu, Shaon Joy, Charles Packianathan, Arthur Laganowsky, Kevin Burgess

Org Biomol Chem· March 2022

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Functional characterization of the methylarsenite-inducible arsRM operon from Noviherbaspirillum denitrificans HC18.
Jun Zhang, Jian Chen, Yi-Fei Wu, Xia Liu, Charles Packianathan

Environ Microbiol· February 2022

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Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.
Zahra Moghadamchargari, Mehdi Shirzadeh, Chang Liu, Samantha Schrecke, Charles Packianathan

Proc Natl Acad Sci U S A· March 2021

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Selective regulation of human TRAAK channels by biologically active phospholipids.
Samantha Schrecke, Yun Zhu, Jacob W McCabe, Mariah Bartz, Charles Packianathan

Nat Chem Biol· January 2021

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Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression.
Chandrasekaran Prabaharan, Palani Kandavelu, Charles Packianathan, Barry P Rosen, Saravanamuthu Thiyagarajan

J Struct Biol· August 2019

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The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.
Charles Packianathan, Palani Kandavelu, Barry P Rosen

Biochemistry· July 2018

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Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) -Adenosylmethionine Methyltransferase Reaction.
Charles Packianathan, Jiaojiao Li, Palani Kandavelu, Banumathi Sankaran, Barry P Rosen

ACS Omega· March 2018

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Arsenic methylation by a novel ArsM As(III) S-adenosylmethionine methyltransferase that requires only two conserved cysteine residues.
Ke Huang, Yan Xu, Charles Packianathan, Fan Gao, Chuan Chen

Mol Microbiol· January 2018

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Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity.
Jiaojiao Li, Charles Packianathan, Toby G Rossman, Barry P Rosen

Chem Res Toxicol· July 2017

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High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity.
Hui Dong, Wenzhong Xu, Jitesh K Pillai, Charles Packianathan, Barry P Rosen

Anal Biochem· July 2015

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A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase.
Kavitha Marapakala, Charles Packianathan, A Abdul Ajees, Dharmendra S Dheeman, Banumathi Sankaran

Acta Crystallogr D Biol Crystallogr· March 2015

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Pathway of human AS3MT arsenic methylation.
Dharmendra S Dheeman, Charles Packianathan, Jitesh K Pillai, Barry P Rosen

Chem Res Toxicol· November 2014

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Crystallization and preliminary X-ray crystallographic studies of CrArsM, an arsenic(III) S-adenosylmethionine methyltransferase from Chlamydomonas reinhardtii.
Charles Packianathan, Jitesh K Pillai, Ahmed Riaz, Palani Kandavelu, Banumathi Sankaran

Acta Crystallogr F Struct Biol Commun· October 2014

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Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities.
Sandra M Lopez, Myles C Hodgson, Charles Packianathan, Ozlem Bingol-Ozakpinar, Fikriye Uras

Biochem Biophys Res Commun· October 2013

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Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.
Mohamad Hamdi, Masafumi Yoshinaga, Charles Packianathan, Jie Qin, Janell Hallauer

Toxicol Appl Pharmacol· July 2012

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Structure of an As(III) S-adenosylmethionine methyltransferase: insights into the mechanism of arsenic biotransformation.
A Abdul Ajees, Kavitha Marapakala, Charles Packianathan, Banumathi Sankaran, Barry P Rosen

Biochemistry· July 2012

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Conformational changes in the hepatitis B virus core protein are consistent with a role for allostery in virus assembly.
Charles Packianathan, Sarah P Katen, Charles E Dann, Adam Zlotnick

J Virol· February 2010

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A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly.
Christina R Bourne, Sarah P Katen, Matthew R Fulz, Charles Packianathan, Adam Zlotnick

Biochemistry· March 2009

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Purification, crystallization and preliminary analysis of hemoglobin from rabbit (Oryctolagus cuniculus).
Sigamani Sundaresan, Packianathan Charles, Kamariah Neelagandan, Mondikalipudur Nanjappa Gounder Ponnuswamy

Protein Pept Lett· July 2008

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