Publications by authors named "Packiarajan Mathivanan"

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Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model.
Yu Wang, Lei Yu, Kaiwen Deng, Mathivanan Packiarajan, Angelo Aguilar

Blood· July 2025

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Radiosynthesis and in Vivo Evaluation of Neuropeptide Y5 Receptor (NPY5R) PET Tracers.
J S Dileep Kumar, Mary Walker, Mathivanan Packiarajan, Vrej Jubian, Jaya Prabhakaran

ACS Chem Neurosci· May 2016

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Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators.
Mathivanan Packiarajan, Michel Grenon, Samuel Zorn, Allen T Hopper, Andrew D White

Bioorg Med Chem Lett· July 2013

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Azetidinyl oxadiazoles as potent mGluR5 positive allosteric modulators.
Mathivanan Packiarajan, Christine G Mazza Ferreira, Sang-Phyo Hong, Andrew D White, Gamini Chandrasena

Bioorg Med Chem Lett· October 2012

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N-Aryl pyrrolidinonyl oxadiazoles as potent mGluR5 positive allosteric modulators.
Mathivanan Packiarajan, Christine G Mazza Ferreira, Sang-Phyo Hong, Andrew D White, Gamini Chandrasena

Bioorg Med Chem Lett· September 2012

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Indolyl and dihydroindolyl N-glycinamides as potent and in vivo active NPY5 antagonists.
Lingyun Wu, Kai Lu, Mathivanan Packiarajan, Vrej Jubian, Gamini Chandrasena

Bioorg Med Chem Lett· March 2012

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5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists.
Mathivanan Packiarajan, Heather Coate, Mahesh Desai, Hermogenes N Jimenez, Emily J Reinhard

Bioorg Med Chem Lett· November 2011

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Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder.
Mathivanan Packiarajan, Mohammad R Marzabadi, Mahesh Desai, Yalei Lu, Stewart A Noble

Bioorg Med Chem Lett· September 2011

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N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists.
Lingyun Wu, Kai Lu, Mahesh Desai, Mathivanan Packiarajan, Amita Joshi

Bioorg Med Chem Lett· September 2011

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Strategies to lower the Pgp efflux liability in a series of potent indole azetidine MCHR1 antagonists.
Kai Lu, Yu Jiang, Bin Chen, Eman M Eldemenky, Gil Ma, Mathivanan Packiarajan

Bioorg Med Chem Lett· September 2011

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Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility.
Michael J Konkel, Mathivanan Packiarajan, Heidi Chen, Upendra P Topiwala, Hermogenes Jimenez

Bioorg Med Chem Lett· August 2006

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Asymmetric dihydroxylation route to a dipeptide isostere of a protease inhibitor: enantioselective synthesis of the core unit of ritonavir.
Arun K Ghosh, Dongwoo Shin, Packiarajan Mathivanan

Chem Commun (Camb)· January 1999

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-Symmetric chiral bis(oxazoline)-metal complexes in catalytic asymmetric synthesis.
Arun K Ghosh, Packiarajan Mathivanan, John Cappiello

Tetrahedron Asymmetry· January 1998

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SYNTHETIC STUDIES OF ANTITUMOR MACROLIDE LAULIMALIDE: ENANTIOSELECTIVE SYNTHESIS OF THE C-C SEGMENT BY A CATALYTIC HETERO DIELS-ALDER STRATEGY.
Arun K Ghosh, Packiarajan Mathivanan, John Cappiello

Tetrahedron Lett· April 1997

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ASYMMETRIC HETERO DIELS-ALDER REACTIONS OF DANISHEFSKY'S DIENE AND GLYOXYLATE ESTERS CATALYZED BY CHIRAL BISOXAZOLINE DERIVED CATALYSTS.
Arun K Ghosh, Packiarajan Mathivanan, John Cappiello, K Krishnan

Tetrahedron Asymmetry· August 1996

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Conformationally Constrained Bis(oxazoline) Derived Chiral Catalyst : A Highly Effective Enantioselective Diels-Alder Reaction.
Arun K Ghosh, Packiarajan Mathivanan, John Cappiello

Tetrahedron Lett· May 1996

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ASYMMETRIC DIELS-ALDER REACTION : CIS-1-ARYLSULFONAMIDO-2-INDANOLS AS HIGHLY EFFECTIVE CHIRAL AUXILIARIES.
Arun K Ghosh, Packiarajan Mathivanan

Tetrahedron Asymmetry· February 1996

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