Publications by authors named "Palwinder Mander"

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Integrated metabolic-transcriptomic network identifies immunometabolic modulations in human macrophages.
Hung-Jen Chen, Daniel C Sévin, Guillermo R Griffith, Johanna Vappiani, Lee M Booty, Palwinder K Mander

Cell Rep· September 2024

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A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn's Disease.
Ahmed M I Elfiky, Ishtu L Hageman, Marte A J Becker, Jan Verhoeff, Andrew Y F Li Yim, Palwinder K Mander

Cells· September 2022

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Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease.
Ahmed M I Elfiky, Mohammed Ghiboub, Andrew Y F Li Yim, Ishtu L Hageman, Jan Verhoeff, Palwinder K Mander

J Crohns Colitis· May 2022

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A randomized study of the safety and pharmacokinetics of GSK3358699, a mononuclear myeloid-targeted bromodomain and extra-terminal domain inhibitor.
Jack A Brown, Joanne Bal, Monica Simeoni, Peter Williams, Palwinder K Mander

Br J Clin Pharmacol· May 2022

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Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility.
Julie A Douthwaite, Christopher A Brown, John R Ferdinand, Rahul Sharma, Jane Elliott, Palwinder K Mander

Sci Rep· February 2022

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IFN-γ Drives Human Monocyte Differentiation into Highly Proinflammatory Macrophages That Resemble a Phenotype Relevant to Psoriasis.
Rosario Luque-Martin, Davina C Angell, Mathias Kalxdorf, Sharon Bernard, William Thompson, Palwinder K Mander

J Immunol· July 2021

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Classic and new mediators for in vitro modelling of human macrophages.
Rosario Luque-Martin, Palwinder K Mander, Pieter J M Leenen, Menno P J Winther

J Leukoc Biol· March 2021

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Pharmacological validation of targets regulating CD14 during macrophage differentiation.
Gisela Jimenez-Duran, Rosario Luque-Martin, Meghana Patel, Emma Koppe, Sharon Bernard, Palwinder K Mander

EBioMedicine· November 2020

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Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
Adam P Cribbs, Stefan Terlecki-Zaniewicz, Martin Philpott, Jeroen Baardman, David Ahern, Palwinder K Mander

Proc Natl Acad Sci U S A· March 2020

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Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis.
Rosario Luque-Martin, Jan Van den Bossche, Rebecca C Furze, Annette E Neele, Saskia van der Velden, Palwinder K Mander

Front Pharmacol· October 2019

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BET Inhibition Improves NASH and Liver Fibrosis.
Sarah A Middleton, Neetu Rajpal, Leanne Cutler, Palwinder Mander, Inmaculada Rioja

Sci Rep· November 2018

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Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
Wenxian Fu, Julia Farache, Susan M Clardy, Kimie Hattori, Palwinder Mander

Elife· November 2014

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Kruidenier et al. reply.
Laurens Kruidenier, Chun-wa Chung, Zhongjun Cheng, John Liddle, KaHing Che, Palwinder K Mander

Nature· October 2014

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Phagocytosis executes delayed neuronal death after focal brain ischemia.
Jonas J Neher, Julius V Emmrich, Michael Fricker, Palwinder K Mander, Clotilde Théry

Proc Natl Acad Sci U S A· October 2013

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Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group.
Mercedes Lobera, Kevin P Madauss, Denise T Pohlhaus, Quentin G Wright, Mark Trocha, Palwinder K Mander

Nat Chem Biol· May 2013

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Laurens Kruidenier, Chun-wa Chung, Zhongjun Cheng, John Liddle, KaHing Che, Palwinder K Mander

Nature· August 2012

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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain.
Penny C Staton, Jon P Hatcher, Deborah J Walker, Alastair D Morrison, Ellen M Shapland, Palwinder K Mander

Pain· September 2008

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Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study.
Aiste Jekabsone, Palwinder K Mander, Anna Tickler, Martyn Sharpe, Guy C Brown

J Neuroinflammation· September 2006

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Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase.
Palwinder K Mander, Aiste Jekabsone, Guy C Brown

J Immunol· January 2006

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Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration.
Palwinder Mander, Guy C Brown

J Neuroinflammation· September 2005

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Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death.
Palwinder Mander, Vilma Borutaite, Salvador Moncada, Guy C Brown

J Neurosci Res· March 2005

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