Publications by authors named "Pamela Powell"

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Plasma Exosome Hemoglobin Released During Surgery Is Associated With Cardiac Injury in Animal Model.
Kyle W Eudailey, Betty Pat, Joo-Yeun Oh, Pamela C Powell, James F Collawn

Ann Thorac Surg· October 2023

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Mitochondrial haplotype modulates genome expression and mitochondrial structure/function in cardiomyocytes following volume overload.
Jason L Guichard, Mariame Selma Kane, Maximiliano Grenett, Michael Sandel, Gloria A Benavides, Pamela Cox Powell

Am J Physiol Heart Circ Physiol· April 2023

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Impact of early pericardial fluid chymase activation after cardiac surgery.
Brittany Butts, Lee A Goeddel, Jingyi Zheng, Betty Pat, Pamela Powell

Front Cardiovasc Med· April 2023

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Red blood cell exosome hemoglobin content increases after cardiopulmonary bypass and mediates acute kidney injury in an animal model.
Betty Pat, Joo-Yeun Oh, Juan Xavier Masjoan Juncos, Pamela C Powell, James F Collawn

J Thorac Cardiovasc Surg· December 2022

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Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation.
Mustafa I Ahmed, Efstathia Andrikopoulou, Jingyi Zheng, Elena Ulasova, Betty Pat, Pamela Cox Powell

JACC Basic Transl Sci· October 2022

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Chronic cardiac structural damage, diastolic and systolic dysfunction following acute myocardial injury due to bromine exposure in rats.
Juan Xavier Masjoan Juncos, Shazia Shakil, Wayne E Bradley, Chih-Chang Wei, Iram Zafar, Pamela Powell

Arch Toxicol· January 2021

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Chymase uptake by cardiomyocytes results in myosin degradation in cardiac volume overload.
Pamela C Powell, Chih-Chang Wei, Lianwu Fu, Betty Pat, Wayne E Bradley

Heliyon· April 2019

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Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats.
Shama Ahmad, Juan Xavier Masjoan Juncos, Aftab Ahmad, Ahmed Zaky, Chih-Chang Wei, Pamela Powell

Am J Physiol Heart Circ Physiol· January 2019

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Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure.
Jason L Guichard, Michael Rogowski, Giulio Agnetti, Lianwu Fu, Pamela Powell

Am J Physiol Heart Circ Physiol· July 2017

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Disruption of desmin-mitochondrial architecture in patients with regurgitant mitral valves and preserved ventricular function.
Mustafa I Ahmed, Jason L Guichard, Rajasekaran Namakkal Soorappan, Shama Ahmad, Nithya Mariappan, Pamela Cox Powell

J Thorac Cardiovasc Surg· October 2016

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Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload.
Lianwu Fu, Chih-Chang Wei, Pamela C Powell, Wayne E Bradley, Sarfaraz Ahmad

J Mol Cell Cardiol· March 2016

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Volume overload induces autophagic degradation of procollagen in cardiac fibroblasts.
Lianwu Fu, Chih-Chang Wei, Pamela C Powell, Wayne E Bradley, James F Collawn

J Mol Cell Cardiol· December 2015

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Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog.
Junying Zheng, Chih-Chang Wei, Naoki Hase, Ke Shi, Cheryl R Killingsworth, Pamela C Powell

PLoS One· January 2015

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Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy.
Justin Barnes, Betty Pat, Yuan-Wen Chen, Pamela C Powell, Wayne E Bradley

Ther Adv Cardiovasc Dis· June 2014

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Increased sarcolipin expression and adrenergic drive in humans with preserved left ventricular ejection fraction and chronic isolated mitral regurgitation.
Junying Zheng, Danielle M Yancey, Mustafa I Ahmed, Chih-Chang Wei, Pamela C Powell

Circ Heart Fail· January 2014

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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart.
Susan A Marsh, Pamela C Powell, Louis J Dell'italia, John C Chatham

Life Sci· March 2013

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Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss.
Chih-Chang Wei, Yuanwen Chen, Lindsay C Powell, Junying Zheng, Ke Shi, Pamela C Powell

PLoS One· November 2012

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Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload.
Yuan-Wen Chen, Betty Pat, James D Gladden, Junying Zheng, Pamela Powell

Am J Physiol Heart Circ Physiol· June 2011

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Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload.
Elena Ulasova, James D Gladden, Yuanwen Chen, Junying Zheng, Betty Pat, Pamela Powell

J Mol Cell Cardiol· January 2011

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Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.
Betty Pat, Yuanwen Chen, Cheryl Killingsworth, James D Gladden, Ke Shi, Pamela C Powell

Circulation· October 2010

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Mast cell stabilization decreases cardiomyocyte and LV function in dogs with isolated mitral regurgitation.
Betty Pat, Cheryl Killingsworth, Yuanwen Chen, James D Gladden, Greg Walcott, Pamela C Powell

J Card Fail· September 2010

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Tumor necrosis factor-alpha produced in cardiomyocytes mediates a predominant myocardial inflammatory response to stretch in early volume overload.
Yuanwen Chen, Betty Pat, Junying Zheng, Laura Cain, Pamela Powell

J Mol Cell Cardiol· July 2010

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Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents.
Chih-Chang Wei, Naoki Hase, Yukiko Inoue, Eddie W Bradley, Eiji Yahiro, Pamela C Powell

J Clin Invest· April 2010

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Increased oxidative stress and cardiomyocyte myofibrillar degeneration in patients with chronic isolated mitral regurgitation and ejection fraction >60%.
Mustafa I Ahmed, James D Gladden, Silvio H Litovsky, Steven G Lloyd, Himanshu Gupta, Pamela Powell

J Am Coll Cardiol· February 2010

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Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog.
Junying Zheng, Yuanwen Chen, Betty Pat, Louis A Dell'italia, Michael Tillson, Pamela C Powell

Circulation· April 2009

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