Publications by authors named "Parvez Alam"

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Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets.
Byron Caughey, Efrosini Artikis, Daniel Shoup, Christina D Orrú, Parvez Alam

Microbiol Mol Biol Rev· December 2025

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Material characterization of the Turkana Abarait.
Kate Parkinson, Parvez Alam

R Soc Open Sci· November 2025

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"Body-first" dementia with Lewy bodies.
David S Goldstein, Courtney Holmes, Patti Sullivan, Risa Isonaka, Dragan Maric, Parvez Alam

Clin Auton Res· August 2025

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Evidence against efficient spontaneous disassembly of prions into small oligomers.
Daniel Shoup, Andrew G Hughson, Brent Race, Parvez Alam, Daniel Dulebohn

J Biol Chem· August 2025

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Elevated Cerebrospinal Fluid α-Synuclein Seeding Activity Predicts Central Lewy Body Diseases.
David S Goldstein, Parvez Alam, Patti Sullivan, Courtney Holmes, Janna Gelsomino

Mov Disord Clin Pract· May 2025

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Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer's disease.
Jesus Campagna, Sujyoti Chandra, Bruce Teter, Whitaker Cohn, Johnny Pham, Parvez Alam

Sci Rep· April 2025

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How Do Molecular Crowders Influence Ligand Binding Kinetics with G-Quadruplex DNA? The Role of Bound Water.
Parvez Alam, Ajay Kumar Chand, Harsh Sahu, Mostofa Ataur Rohman, Ndege Simisi Clovis

J Phys Chem B· March 2025

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A same day α-synuclein RT-QuIC seed amplification assay for synucleinopathy biospecimens.
Sabiha Parveen, Parvez Alam, Christina D Orrù, Sarah Vascellari, Andrew G Hughson

NPJ Biosens· February 2025

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Effect of Divalent Cations on Polarity and Hydration at the Lipid/Water Interface Probed by 4-Aminophthalimide-Based Dyes.
Parvez Alam, Pramod Kumar, Harsh Sahu, Deepika Sardana, Pronab Kundu

J Phys Chem B· January 2025

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The ER-Resident Ras Inhibitor 1 (Eri1) of Inhibits Hyphal Morphogenesis via the Ras-Independent cAMP-PKA Pathway.
Subhash Chandra Sethi, Monika Bharati, Yatin Kumar, Usha Yadav, Harshita Saini, Parvez Alam

ACS Infect Dis· October 2024

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Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries.
Mikkel Roland Holst, Mette Richner, Pernille Olsgaard Arenshøj, Parvez Alam, Kathrine Hyldig

Fluids Barriers CNS· October 2024

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Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer.
Parvez Alam, Forrest Hoyt, Efrosini Artikis, Jakub Soukup, Andrew G Hughson

Acta Neuropathol· October 2024

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Quantifying Membrane Alterations with Tailored Fluorescent Dyes: A Rapid Antibiotic Resistance Profiling Methodology.
Ashim Kumar Dubey, Deepika Sardana, Taru Verma, Parvez Alam, Avik Chattopadhyay

ACS Infect Dis· August 2024

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Mode III Tear Resistance of Silk Cocoons.
Ateeq Ur Rehman, Vasileios Koutsos, Parvez Alam

ACS Mater Au· July 2024

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Effect of molecular crowders on ligand binding kinetics with G-quadruplex DNA probed by fluorescence correlation spectroscopy.
Parvez Alam, Ndege Simisi Clovis, Ajay Kumar Chand, Mohammad Firoz Khan, Sobhan Sen

Methods Appl Fluoresc· July 2024

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Peristaltic Motion Enabled by Pneumatic Artificial Muscles (PAMs) as Structural "Soft-Stiff" Actuators in a Modular Worm-Inspired Robot.
Beth Tinsley, Sergio Caponi, Lucy McAteer, Gleb Nebesnyy, Dean Sammanthan, Parvez Alam

Biomimetics (Basel)· July 2024

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Hotspot site microenvironment in the deubiquitinase OTUB1 drives its stability and aggregation.
Sushanta Majumder, Mitul Srivastava, Parvez Alam, Sandhini Saha, Raniki Kumari

J Biol Chem· June 2024

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Seeding activity of human superoxide dismutase 1 aggregates in familial and sporadic amyotrophic lateral sclerosis postmortem neural tissues by real-time quaking-induced conversion.
Justin K Mielke, Mikael Klingeborn, Eric P Schultz, Erin L Markham, Emily D Reese, Parvez Alam

Acta Neuropathol· June 2024

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Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning.
Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava

Nat Chem Biol· May 2024

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Unusual similarity of DNA solvation dynamics in high-salinity crowding with divalent cations of varying concentrations.
Deepika Sardana, Parvez Alam, Kavita Yadav, Ndege Simisi Clovis, Pramod Kumar

Phys Chem Chem Phys· October 2023

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The influence of claw morphology on gripping efficiency.
Graham Turnbull, Sutejas Chari, Zehao Li, Ziyue Yang, Catharina Maria Alam, Parvez Alam

Biol Open· May 2023

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From trash to treasure: Sourcing high-value, sustainable cellulosic materials from living bioreactor waste streams.
Thomas R Harrison, Vijai Kumar Gupta, Parvez Alam, Adam Willis Perriman, Fabrizio Scarpa

Int J Biol Macromol· April 2023

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Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions.
Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen

Chem Sci· March 2023

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A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers.
Mitra Pirhaghi, Signe Andrea Frank, Parvez Alam, Janni Nielsen, Vita Sereikaite

J Biol Chem· December 2022

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Cryo-EM of prion strains from the same genotype of host identifies conformational determinants.
Forrest Hoyt, Parvez Alam, Efrosini Artikis, Cindi L Schwartz, Andrew G Hughson

PLoS Pathog· November 2022

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