Publications by authors named "Pascal Degrace"

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Blockade of cannabinoid CB receptors potentiates the anti-fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Patricia Passilly-Degrace, Pascal Degrace

Br J Pharmacol· November 2025

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A Simplified and Robust Model for the Study of Diabetic Nephropathy: Streptozotocin-Induced Diabetic Mice Fed a High-Protein Diet.
Océane Pointeau, Romain Barbosa, Maéva Loriot, Julia Leemput, Elisabeth Dubus, Patricia Passilly-Degrace, Pascal Degrace

Int J Mol Sci· March 2025

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Impaired unsaturated fatty acid elongation alters mitochondrial function and accelerates metabolic dysfunction-associated steatohepatitis progression.
Adrien Vouilloz, Thibaut Bourgeois, Marc Diedisheim, Thomas Pilot, Antoine Jalil, Pascal Degrace

Metabolism· January 2025

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Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of Raptor in zebrafish.
Wen-Hao Zhou, Yuan Luo, Rui-Xin Li, Pascal Degrace, Tony Jourdan

J Biol Chem· October 2023

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Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy.
Laetitia Jacquot, Océane Pointeau, Célia Roger-Villeboeuf, Patricia Passilly-Degrace, Rim Belkaid, Pascal Degrace

Front Nephrol· March 2023

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Chemical Synthesis, Pharmacokinetic Properties and Biological Effects of JM-00266, a Putative Non-Brain Penetrant Cannabinoid Receptor 1 Inverse Agonist.
Tania Muller, Laurent Demizieux, Stéphanie Troy-Fioramonti, Chloé Buch, Julia Leemput, Patricia Passilly-Degrace, Pascal Degrace

Int J Mol Sci· March 2022

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Endocannabinoids Produced by White Adipose Tissue Modulate Lipolysis in Lean but Not in Obese Rodent and Human.
Chloé Buch, Tania Muller, Julia Leemput, Patricia Passilly-Degrace, Pablo Ortega-Deballon, Pascal Degrace

Front Endocrinol (Lausanne)· February 2022

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Liraglutide Increases the Catabolism of Apolipoprotein B100-Containing Lipoproteins in Patients With Type 2 Diabetes and Reduces Proprotein Convertase Subtilisin/Kexin Type 9 Expression.
Bruno Vergès, Laurence Duvillard, Jean Paul Pais de Barros, Benjamin Bouillet, Sabine Baillot-Rudoni, Pascal Degrace

Diabetes Care· April 2021

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Simultaneous Inhibition of Peripheral CB1R and iNOS Mitigates Obesity-Related Dyslipidemia Through Distinct Mechanisms.
Célia Roger, Chloé Buch, Tania Muller, Julia Leemput, Laurent Demizieux, Patricia Passilly-Degrace, Pascal Degrace

Diabetes· October 2020

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Mitochondrial Fatty Acid β-Oxidation Inhibition Promotes Glucose Utilization and Protein Deposition through Energy Homeostasis Remodeling in Fish.
Ling-Yu Li, Jia-Min Li, Li-Jun Ning, Dong-Liang Lu, Yuan Luo, Pascal Degrace

J Nutr· September 2020

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Functional differences between l- and d-carnitine in metabolic regulation evaluated using a low-carnitine Nile tilapia model.
Jia-Min Li, Ling-Yu Li, Yu-Xue Zhang, Zhe-Yue Jiang, Samwel M Limbu, Pascal Degrace

Br J Nutr· September 2019

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Liraglutide Reduces Postprandial Hyperlipidemia by Increasing ApoB48 (Apolipoprotein B48) Catabolism and by Reducing ApoB48 Production in Patients With Type 2 Diabetes Mellitus.
Bruno Vergès, Laurence Duvillard, Jean Paul Pais de Barros, Benjamin Bouillet, Sabine Baillot-Rudoni, Pascal Degrace

Arterioscler Thromb Vasc Biol· September 2018

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Orosensory Detection of Dietary Fatty Acids Is Altered in CB₁R Mice.
Léa Brissard, Julia Leemput, Aziz Hichami, Patricia Passilly-Degrace, Guillaume Maquart, Pascal Degrace

Nutrients· September 2018

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Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.
Jia-Min Li, Ling-Yu Li, Xuan Qin, Pascal Degrace, Laurent Demizieux

Front Physiol· May 2018

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Inhibited fatty acid β-oxidation impairs stress resistance ability in Nile tilapia (Oreochromis niloticus).
Han Pan, Ling-Yu Li, Jia-Min Li, Wei-Li Wang, Samwel Mchele Limbu, Pascal Degrace

Fish Shellfish Immunol· September 2017

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Overactivation of the endocannabinoid system alters the antilipolytic action of insulin in mouse adipose tissue.
Tania Muller, Laurent Demizieux, Stéphanie Troy-Fioramonti, Joseph Gresti, Jean-Paul Pais de Barros, Pascal Degrace

Am J Physiol Endocrinol Metab· July 2017

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Early Low-Fat Diet Enriched With Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High-Fat Diet Challenge in Mice.
Laurent Demizieux, Fabiana Piscitelli, Stephanie Troy-Fioramonti, Fabio Arturo Iannotti, Simona Borrino, Pascal Degrace

Diabetes· July 2016

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Acute activation of cannabinoid receptors by anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice.
Stephanie Troy-Fioramonti, Laurent Demizieux, Joseph Gresti, Tania Muller, Bruno Vergès, Pascal Degrace

Diabetes· March 2015

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Disturbances in cholesterol, bile acid and glucose metabolism in peroxisomal 3-ketoacylCoA thiolase B deficient mice fed diets containing high or low fat contents.
Valérie Nicolas-Francès, Ségolène Arnauld, Jacques Kaminski, Emiel Ver Loren van Themaat, Marie-Claude Clémencet, Pascal Degrace

Biochimie· March 2014

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Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity.
Zhen-Yu Du, Tao Ma, Bjørn Liaset, Alison H Keenan, Pedro Araujo, Pascal Degrace

Biochim Biophys Acta· February 2013

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Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: evidence from cultured explants.
Tony Jourdan, Laurent Demizieux, Joseph Gresti, Louiza Djaouti, Lila Gaba, Pascal Degrace

Hepatology· March 2012

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Luminal lipid regulates CD36 levels and downstream signaling to stimulate chylomicron synthesis.
Thi Thu Trang Tran, Hélène Poirier, Lionel Clément, Fatiha Nassir, Maurice M A L Pelsers, Pascal Degrace

J Biol Chem· July 2011

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Vaccenic and elaidic acid equally esterify into triacylglycerols, but differently into phospholipids of fed rat liver cells.
Zhen-Yu Du, Pascal Degrace, Joseph Gresti, Olivier Loreau, Pierre Clouet

Lipids· July 2011

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A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα-mediated upregulation of SREBP-2 target genes in the liver.
Marco Fidaleo, Ségolène Arnauld, Marie-Claude Clémencet, Grégory Chevillard, Marie-Charlotte Royer, Pascal Degrace

Biochimie· May 2011

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Dissimilar properties of vaccenic versus elaidic acid in beta-oxidation activities and gene regulation in rat liver cells.
Zhen-Yu Du, Pascal Degrace, Joseph Gresti, Olivier Loreau, Pierre Clouet

Lipids· July 2010

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