Publications by authors named "Pascal Gottmann"

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Adipose tissue-derived microRNAs as epigenetic modulators of type 2 diabetes.
Ratika Sehgal, Neele Haacke, Alice Maguolo, Fiorella A Solari, Markus Jähnert, Pascal Gottmann

BMC Med· December 2025

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Nutritional hyperketonemia by dietary medium-chain fatty acids is driven by the liver without contribution from the intestine.
Ye Cao, Kyle Feola, Pascal Gottmann, Stephanie K Holm, Ricardo Monroy

bioRxiv· October 2025

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Three-protein signature is associated with baseline and persistently elevated or recurrent depressive symptoms in individuals with recent-onset diabetes.
Maria C Spagnuolo, Pascal Gottmann, Jana Sommer, Sandra Olivia Borgmann, Klaus Strassburger

BMJ Open Diabetes Res Care· February 2025

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Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease.
Yun Kwon, Pascal Gottmann, Surui Wang, Joel Tissink, Karsten Motzler

J Hepatol· January 2025

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Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse models.
Pascal Gottmann, Thilo Speckmann, Mandy Stadion, Prateek Chawla, Judith Saurenbach

Diabetologia· January 2025

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Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Adriana Miranda-Cervantes, Andreas M Fritzen, Steffen H Raun, Ondřej Hodek, Lisbeth L V Møller, Pascal Gottmann

Nat Commun· January 2025

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Novel markers and networks related to restored skeletal muscle transcriptome after bariatric surgery.
Meriem Ouni, Leona Kovac, Sofiya Gancheva, Markus Jähnert, Erika Zuljan, Pascal Gottmann

Obesity (Silver Spring)· February 2024

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Identification of MicroRNAs Associated with Prediabetic Status in Obese Women.
Leona Kovac, Thilo Speckmann, Markus Jähnert, Pascal Gottmann, Louise Fritsche

Int J Mol Sci· October 2023

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Differences in DNA methylation of HAMP in blood cells predicts the development of type 2 diabetes.
Meriem Ouni, Fabian Eichelmann, Markus Jähnert, Christin Krause, Sophie Saussenthaler, Pascal Gottmann

Mol Metab· September 2023

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Alterations of Lipid Profile in Livers with Impaired Lipophagy.
Wenke Jonas, Kristin Schwerbel, Lisa Zellner, Markus Jähnert, Pascal Gottmann

Int J Mol Sci· October 2022

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Heterogeneous Development of β-Cell Populations in Diabetes-Resistant and -Susceptible Mice.
Pascal Gottmann, Thilo Speckmann, Mandy Stadion, Erika Zuljan, Heja Aga

Diabetes· September 2022

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Identification of Novel Genes Involved in Hyperglycemia in Mice.
Wenke Jonas, Oliver Kluth, Anett Helms, Sarah Voß, Markus Jähnert, Pascal Gottmann

Int J Mol Sci· March 2022

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Distinct Adipogenic and Fibrogenic Differentiation Capacities of Mesenchymal Stromal Cells from Pancreas and White Adipose Tissue.
Heja Aga, George Soultoukis, Mandy Stadion, Francisco Garcia-Carrizo, Markus Jähnert, Pascal Gottmann

Int J Mol Sci· February 2022

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Insulin Directly Regulates the Circadian Clock in Adipose Tissue.
Neta Tuvia, Olga Pivovarova-Ramich, Veronica Murahovschi, Sarah Lück, Astrid Grudziecki, Pascal Gottmann

Diabetes· September 2021

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MiR-205 is up-regulated in islets of diabetes-susceptible mice and targets the diabetes gene Tcf7l2.
Meriem Ouni, Pascal Gottmann, Efraim Westholm, Kristin Schwerbel, Markus Jähnert

Acta Physiol (Oxf)· August 2021

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Overexpression of Gjb4 impairs cell proliferation and insulin secretion in primary islet cells.
Anneke Gässler, Charline Quiclet, Oliver Kluth, Pascal Gottmann, Kristin Schwerbel

Mol Metab· November 2020

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Epigenetic Changes in Islets of Langerhans Preceding the Onset of Diabetes.
Meriem Ouni, Sophie Saussenthaler, Fabian Eichelmann, Markus Jähnert, Mandy Stadion, Pascal Gottmann

Diabetes· November 2020

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Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.
Kristin Schwerbel, Anne Kamitz, Natalie Krahmer, Nicole Hallahan, Markus Jähnert, Pascal Gottmann

J Hepatol· October 2020

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Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning.
Heja Aga, Nicole Hallahan, Pascal Gottmann, Markus Jaehnert, Sophie Osburg

Front Genet· September 2020

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Polymorphisms in miRNA binding sites involved in metabolic diseases in mice and humans.
Pascal Gottmann, Meriem Ouni, Lisa Zellner, Markus Jähnert, Kilian Rittig

Sci Rep· April 2020

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Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans.
Oliver Kluth, Mandy Stadion, Pascal Gottmann, Heja Aga, Markus Jähnert

Cell Rep· March 2019

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Epigenetic regulation of hepatic Dpp4 expression in response to dietary protein.
Sophie Saussenthaler, Meriem Ouni, Christian Baumeier, Kristin Schwerbel, Pascal Gottmann

J Nutr Biochem· January 2019

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Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes.
Clemens Wittenbecher, Meriem Ouni, Olga Kuxhaus, Markus Jähnert, Pascal Gottmann

Diabetes· January 2019

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A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
Heike Vogel, Anne Kamitz, Nicole Hallahan, Sandra Lebek, Tanja Schallschmidt, Pascal Gottmann

Hum Mol Genet· September 2018

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Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis.
Pengfei Xu, Jens-Uwe Werner, Sebastian Milerski, Carmen M Hamp, Tatjana Kuzenko, Pascal Gottmann

Front Physiol· June 2018

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