Publications by authors named "Pascal Johann"

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Malignant Rhabdoid Tumors of the Liver Are Associated With Inferior Outcomes Compared to Other Extracranial Rhabdoid Tumors.
Sebastian Bühner, Katharina Gastberger, Stefanie Tüchert-Knoll, Victoria E Fincke, Pascal D Johann

Pediatr Blood Cancer· December 2025

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In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery.
Nicole C Riedel, Carolin Walter, Flavia W de Faria, Lea Altendorf, Paula Aust, Pascal Johann

Cancer Commun (Lond)· December 2025

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Multi-modal omics analysis of a paediatric melanoma highlights mechanisms underlying treatment resistance.
Marlena Mucha, Sebastian Bühner, Maurice Loßner, Victoria E Fincke, Nic G Reitsam, Pascal D Johann

Commun Med (Lond)· October 2025

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A rare case of atypical teratoid rhabdoid tumor (AT/RT) with homozygous SMARCB1 loss and one concurrent somatic heterozygous SMARCA4 variant.
Ylvi Müller, Sebastian Bühner, Victoria Fincke, Katrin Mauch-Mücke, Markus J Riemenschneider, Pascal Johann

Acta Neuropathol Commun· October 2025

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Malignant Rhabdoid Tumors of Cranial Nerves-A Clinically Distinct Group With Characteristic Neuroradiological, Histopathological, and Molecular Features.
Miriam Gruhle, Brigitte Bison, Katharina Gastberger, Pascal D Johann, Irene Teichert von Lüttichau

Pediatr Blood Cancer· August 2025

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A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories.
Enrique Blanco-Carmona, Irene Paassen, Jiayou He, Jeff DeMartino, Annette Büllesbach, Pascal D Johann

Neuro Oncol· July 2025

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Mutational Spectrum in Intracranial CNS-Neoplasias-A Review and a Report from the CNS-InterREST GPOH Study Center.
Selma Manea, Victoria E Fincke, Michael C Frühwald, Dominik Sturm, Barbara von Zezschwitz, Pascal D Johann

Cancers (Basel)· April 2025

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Clinical and Molecular Risk Factors in Extracranial Malignant Rhabdoid Tumors: Toward an Integrated Model of High-Risk Tumors.
Victoria E Fincke, Mona Steinbügl, Hye-Jung E Chun, Karolina Nemes, Marlena Mucha, Pascal D Johann

Clin Cancer Res· October 2024

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Embryonal tumor with multilayered rosettes located in the brainstem: Promising results after multimodal treatment including interstitial brachytherapy.
Stephanie Theresa Jünger, Daniel Rueß, Christoph Kabbasch, Gerrit H Gielen, Torsten Pietsch, Pascal Johann

Neurooncol Pract· April 2024

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Human-Level Differentiation of Medulloblastoma from Pilocytic Astrocytoma: A Real-World Multicenter Pilot Study.
Benedikt Wiestler, Brigitte Bison, Lars Behrens, Stefanie Tüchert, Marie Metz, Pascal Johann

Cancers (Basel)· April 2024

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Rhabdoid tumors in patients conceived following ART: is there an association?
Karolina Nemes, Martin Benesch, Julia Kolarova, Pascal Johann, Martin Hasselblatt

Hum Reprod· October 2023

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Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
Pascal D Johann, Lea Altendorf, Emma-Maria Efremova, Till Holsten, Mona Steinbügl

Acta Neuropathol· September 2023

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Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours.
Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A Oldridge, Sumedha Sudhaman, Pascal D Johann

Genome Med· September 2023

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"Adult rhabdoid tumors-a riddle inside an enigma?".
Pascal D Johann

Mod Pathol· December 2022

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Outcome for Pediatric Adreno-Cortical Tumors Is Best Predicted by the COG Stage and Five-Item Microscopic Score-Report from the German MET Studies.
Michaela Kuhlen, Marina Kunstreich, Stefan A Wudy, Paul-Martin Holterhus, Lienhard Lessel, Pascal D Johann

Cancers (Basel)· December 2022

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DNA methylation-based classification of sinonasal tumors.
Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Pascal D Johann

Nat Commun· November 2022

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Renal Medullary Carcinomas Harbor a Distinct Methylation Phenotype and Display Aberrant Methylation of Genes Related to Early Nephrogenesis.
Victoria E Fincke, Mateja E Krulik, Piyush Joshi, Michael C Frühwald, Ying-Bei Chen, Pascal D Johann

Cancers (Basel)· October 2022

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SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome.
Martin Hasselblatt, Christian Thomas, Aniello Federico, Karolina Nemes, Pascal D Johann

Am J Surg Pathol· September 2022

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Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.
Lena Blümel, Nan Qin, Johannes Berlandi, Eunice Paisana, Rita Cascão, Pascal D Johann

Cell Death Dis· September 2022

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Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC.
Martin Hasselblatt, Christian Thomas, Aniello Federico, Susanne Bens, Mats Hellström, Pascal D Johann

Neuropathol Appl Neurobiol· June 2022

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ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.
Aniello Federico, Christian Thomas, Katarzyna Miskiewicz, Niklas Woltering, Francesca Zin, Pascal D Johann

Acta Neuropathol· June 2022

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Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population.
Karolina Nemes, Pascal D Johann, Mona Steinbügl, Miriam Gruhle, Susanne Bens

Cancers (Basel)· April 2022

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Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.
Monika Graf, Marta Interlandi, Natalia Moreno, Dörthe Holdhof, Carolin Göbel, Johannes Nowak, Pascal Johann

Nat Commun· March 2022

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Current and Emerging Therapeutic Approaches for Extracranial Malignant Rhabdoid Tumors.
Karolina Nemes, Pascal D Johann, Stefanie Tüchert, Patrick Melchior, Christian Vokuhl

Cancer Manag Res· February 2022

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