Publications by authors named "Pascal Kessler"

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PIK3C2A-Related Clinical Phenotype and Cellular Charaterization Linked to Functional SHH Primary Cilia Defect.
Adella Karam, Clarisse Delvallée, Bénédicte Gérard, Elodie Javey, Pascal Kessler

Clin Genet· December 2025

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FUS Mislocalization Rewires a Cortical Gene Network to Drive Cognitive and Behavioral Impairment in ALS.
Raphaelle Cassel, Félicie Lorenc, Aurélie Bombardier, Claudia DE Tapia, Stéphane Dieterle, Pascal Kessler

medRxiv· June 2025

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Experimental myositis: an optimised version of C-protein-induced myositis.
Margherita Giannini, Daniela Rovito, Mustapha Oulad-Abdelghani, Nadia Messaddeq, Léa Debrut, Pascal Kessler

RMD Open· March 2025

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CREB3 gain of function variants protect against ALS.
Salim Megat, Christine Marques, Marina Hernán-Godoy, Chantal Sellier, Geoffrey Stuart-Lopez, Pascal Kessler

Nat Commun· March 2025

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A Snake Toxin Derivative for Treatment of Hyponatremia and Polycystic Kidney Diseases.
Goran Stanajic-Petrovic, Mathilde Keck, Peggy Barbe, Apolline Urman, Evelyne Correia, Pascal Kessler

J Am Soc Nephrol· February 2025

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Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency.
Jelena Scekic-Zahirovic, Cristina Benetton, Aurore Brunet, XiaoQian Ye, Evgeny Logunov, Pascal Kessler

Sci Transl Med· March 2024

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Unveiling P. vivax invasion pathways in Duffy-negative individuals.
Isabelle Bouyssou, Sara El Hoss, Cécile Doderer-Lang, Matthieu Schoenhals, Lova Tsikiniaina Rasoloharimanana, Pascal Kessler

Cell Host Microbe· December 2023

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A synthetic delivery vector for mucosal vaccination.
Anne Billet, Justine Hadjerci, Thi Tran, Pascal Kessler, Jonathan Ulmer

Biomaterials· November 2023

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Engineered Synthetic STxB for Enhanced Cytosolic Delivery.
Justine Hadjerci, Anne Billet, Pascal Kessler, Gilles Mourier, Marine Ghazarian

Cells· April 2023

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Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor.
Anne-Cécile Van Baelen, Xavier Iturrioz, Marion Chaigneau, Pascal Kessler, Catherine Llorens-Cortes

Int J Mol Sci· January 2023

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From a Cone Snail Toxin to a Competitive MC4R Antagonist.
Steve Reynaud, Suli-Anne Laurin, Justyna Ciolek, Peggy Barbe, Anne-Cécile Van Baelen, Pascal Kessler

J Med Chem· September 2022

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Structural and Functional Diversity of Animal Toxins Interacting With GPCRs.
Anne-Cécile Van Baelen, Philippe Robin, Pascal Kessler, Arhamatoulaye Maïga, Nicolas Gilles

Front Mol Biosci· February 2022

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A snake toxin as a theranostic agent for the type 2 vasopressin receptor.
Laura Droctové, Manon Lancien, Vu Long Tran, Michaël Susset, Benoit Jego, Pascal Kessler

Theranostics· June 2021

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Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism.
Jelena Scekic-Zahirovic, Mathieu Fischer, Geoffrey Stuart-Lopez, Thibaut Burg, Johan Gilet, Pascal Kessler

Prog Neurobiol· May 2021

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Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Pascal Kessler

Nat Commun· May 2021

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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a.
Miguel Salinas, Pascal Kessler, Dominique Douguet, Daad Sarraf, Nicolo Tonali

Neuropharmacology· March 2021

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STIM1 over-activation generates a multi-systemic phenotype affecting the skeletal muscle, spleen, eye, skin, bones and immune system in mice.
Roberto Silva-Rojas, Susan Treves, Hugues Jacobs, Pascal Kessler, Nadia Messaddeq

Hum Mol Genet· May 2019

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Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
Valentina M Lionello, Anne-Sophie Nicot, Maxime Sartori, Christine Kretz, Pascal Kessler

Sci Transl Med· March 2019

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Reducing dynamin 2 (DNM2) rescues -related dominant centronuclear myopathy.
Suzie Buono, Jacob A Ross, Hichem Tasfaout, Yotam Levy, Christine Kretz, Pascal Kessler

Proc Natl Acad Sci U S A· October 2018

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A Method for Parasagittal Sectioning for Neuroanatomical Quantification of Brain Structures in the Adult Mouse.
Stephan C Collins, Christel Wagner, Léo Gagliardi, Perrine F Kretz, Marie-Christine Fischer, Pascal Kessler

Curr Protoc Mouse Biol· September 2018

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Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO.
Antonio Del Vecchio, Fabien Caillé, Arnaud Chevalier, Olivier Loreau, Kaisa Horkka, Pascal Kessler

Angew Chem Int Ed Engl· July 2018

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Expression of the neuropathy-associated MTMR2 gene rescues MTM1-associated myopathy.
Matthieu A Raess, Belinda S Cowling, Dimitri L Bertazzi, Christine Kretz, Bruno Rinaldi, Pascal Kessler

Hum Mol Genet· October 2017

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Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription.
Nikolaos Vosnakis, Marc Koch, Elisabeth Scheer, Pascal Kessler, Yves Mély

EMBO J· September 2017

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The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions.
Pascal Kessler, Pascale Marchot, Marcela Silva, Denis Servent

J Neurochem· August 2017

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A Theranostic Agent Combining a Two-Photon-Absorbing Photosensitizer for Photodynamic Therapy and a Gadolinium(III) Complex for MRI Detection.
Julie Schmitt, Valérie Heitz, Angélique Sour, Frédéric Bolze, Pascal Kessler

Chemistry· February 2016

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