Publications by authors named "Pascal P Therond"

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TMED10 mediates the loading of neosynthesised Sonic Hedgehog in COPII vesicles for efficient secretion and signalling.
Yonis Bare, Tamás Matusek, Sophie Vriz, Maika S Deffieu, Pascal P Thérond

Cell Mol Life Sci· August 2023

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Microvilli-derived extracellular vesicles carry Hedgehog morphogenic signals for Drosophila wing imaginal disc development.
Ilse Hurbain, Anne-Sophie Macé, Maryse Romao, Elodie Prince, Lucie Sengmanivong

Curr Biol· January 2022

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Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development.
Julien Marcetteau, Tamàs Matusek, Frédéric Luton, Pascal P Thérond

Biol Open· December 2021

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Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth.
Sandrine Pizette, Tamás Matusek, Bram Herpers, Pascal P Thérond, Catherine Rabouille

J Cell Sci· May 2021

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The GTPase Rab8 differentially controls the long- and short-range activity of the Hedgehog morphogen gradient by regulating Hedgehog apico-basal distribution.
Tanvi Gore, Tamás Matusek, Gisela D'Angelo, Cécile Giordano, Thomas Tognacci

Development· March 2021

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Circulating Hedgehog: a fresh view of a classic morphogen.
Elodie Prince, Julien Marcetteau, Pascal P Thérond

Development· December 2020

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Functions of Wnt and Hedgehog-containing extracellular vesicles in development and disease.
Tamás Matusek, Julien Marcetteau, Pascal P Thérond

J Cell Sci· September 2020

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Hedgehog Signaling Modulates Glial Proteostasis and Lifespan.
Andrew Rallis, Juan A Navarro, Mathias Rass, Amélie Hu, Serge Birman

Cell Rep· February 2020

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Endocytosis of Hedgehog through dispatched regulates long-range signaling.
Gisela D'Angelo, Tamás Matusek, Sandrine Pizette, Pascal P Thérond

Dev Cell· February 2015

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The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.
Tamás Matusek, Franz Wendler, Sophie Polès, Sandrine Pizette, Gisela D'Angelo

Nature· December 2014

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Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.
Nadia Ranieri, Pascal P Thérond, Laurent Ruel

Nat Commun· October 2014

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The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond

Nat Rev Mol Cell Biol· July 2013

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Dally and Notum regulate the switch between low and high level Hedgehog pathway signalling.
Katie L Ayers, Rana Mteirek, Alexandra Cervantes, Laurence Lavenant-Staccini, Pascal P Thérond

Development· September 2012

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Release and transportation of Hedgehog molecules.
Pascal P Thérond

Curr Opin Cell Biol· April 2012

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Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.
Nadia Ranieri, Laurent Ruel, Armel Gallet, Sophie Raisin, Pascal P Thérond

Dev Cell· February 2012

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Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling.
Katie L Ayers, Pascal P Thérond

Trends Cell Biol· May 2010

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The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum.
Katie L Ayers, Armel Gallet, Laurence Staccini-Lavenant, Pascal P Thérond

Dev Cell· April 2010

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The full-length unprocessed hedgehog protein is an active signaling molecule.
Robert Tokhunts, Samer Singh, Tehyen Chu, Gisela D'Angelo, Valerie Baubet

J Biol Chem· January 2010

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Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli.
Laurent Ruel, Pascal P Thérond

Genes Dev· August 2009

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Confocal analysis of Hedgehog morphogenetic gradient coupled with fluorescent in situ hybridization of hedgehog target genes.
Armel Gallet, Pascal P Thérond

Methods Mol Biol· December 2008

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Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis.
Armel Gallet, Laurence Staccini-Lavenant, Pascal P Thérond

Dev Cell· May 2008

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The role of kinases in the Hedgehog signalling pathway.
Reid A Aikin, Katie L Ayers, Pascal P Thérond

EMBO Rep· April 2008

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Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.
Laurent Ruel, Armel Gallet, Sophie Raisin, Arnaud Truchi, Laurence Staccini-Lavenant

Development· October 2007

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Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia.
Armel Gallet, Laurent Ruel, Laurence Staccini-Lavenant, Pascal P Thérond

Development· February 2006

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Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.
Nathalie Arquier, Paul Vigne, Eric Duplan, Tien Hsu, Pascal P Therond

Biochem J· January 2006

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