Publications by authors named "Pascal Pigeon"

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Self-assemblies of cell-penetrating peptides and ferrocifens: design and biological evaluation of an innovative platform for lung cancer treatment.
Léna Guyon, Abdallah Ladaycia, Agnese Bosio, Laurent Lemaire, Florence Franconi, Pascal Pigeon

Nanoscale· April 2025

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How does ferrocene correlate with ferroptosis? Multiple approaches to explore ferrocene-appended GPX4 inhibitors as anticancer agents.
Wei Li, Jing Yu, Jing Wang, Xuejing Fan, Ximing Xu, Pascal Pigeon

Chem Sci· July 2024

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Deciphering the Diversified Metabolic Behavior of Hydroxyalkyl Ferrocidiphenols as Anticancer Complexes.
Hui Wang, Xuejing Fan, Pei-Pei Xie, Shuang Yang, Pascal Pigeon

J Med Chem· January 2024

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Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study.
Pascal Pigeon, Feten Najlaoui, Michael James McGlinchey, Juan Sanz García, Gérard Jaouen

Int J Mol Sci· July 2023

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Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure.
Pierre Idlas, Elise Lepeltier, Guillaume Bastiat, Pascal Pigeon, Michael J McGlinchey

Langmuir· February 2023

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Ferrocifen stealth LNCs and conventional chemotherapy: A promising combination against multidrug-resistant ovarian adenocarcinoma.
Pierre Idlas, Abdallah Ladaycia, Fariba Némati, Elise Lepeltier, Pascal Pigeon

Int J Pharm· October 2022

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Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of Its Oxidized Derivatives.
Charles Fayolle, Pascal Pigeon, Nathalie Fischer-Durand, Michèle Salmain, Olivier Buriez

Molecules· October 2022

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α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies.
Pascal Pigeon, Marie Gaschard, Mohamed Othman, Michèle Salmain, Gérard Jaouen

Molecules· July 2022

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Succinimido-Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity.
Feten Najlaoui, Benoit Busser, Germain Sotoing Taïwe, Pascal Pigeon, Nathalie Sturm

Molecules· July 2022

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Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells.
Yong Wang, Pascal Pigeon, Wei Li, Jiangkun Yan, Patrick M Dansette

Eur J Med Chem· April 2022

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Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes.
Anne Vessières, Emie Quissac, Nolwenn Lemaire, Agusti Alentorn, Patrycja Domeracka, Pascal Pigeon

Int J Mol Sci· September 2021

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Antimicrobial, Antitumor and Side Effects Assessment of a Newly Synthesized Tamoxifen Analog.
Fatma Abdmouleh, Mehdi El Arbi, Hajer Ben Saad, Karim Jellali, Emna Ketata, Pascal Pigeon

Curr Top Med Chem· June 2021

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Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide-Ferrocifen Self-Assemblies.
Léna Guyon, Elise Lepeltier, Jean-Christophe Gimel, Brice Calvignac, Florence Franconi, Pascal Pigeon

J Phys Chem Lett· November 2019

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Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects.
Federica Tonolo, Michèle Salmain, Valeria Scalcon, Siden Top, Pascal Pigeon

ChemMedChem· October 2019

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Atypical Lone Pair-Ï€ Interaction with Quinone Methides in a Series of Imido-Ferrociphenol Anticancer Drug Candidates.
Yong Wang, Pascal Pigeon, Siden Top, Juan Sanz García, Claire Troufflard

Angew Chem Int Ed Engl· June 2019

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Anticancer properties of lipid and poly(ε-caprolactone) nanocapsules loaded with ferrocenyl-tamoxifen derivatives.
Feten Najlaoui, Pascal Pigeon, Sonia Aroui, Mylène Pezet, Lucie Sancey

J Pharm Pharmacol· November 2018

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Aryl Butenes Active against K562 Cells and Lacking Tyrosinase Inhibitory Activity as New Leads in the Treatment of Leukemia.
Mehdi El Arbi, Emna Ketata, Aref Neifar, Wafa Mihoubi, Girish K Gupta, Pascal Pigeon

Mini Rev Med Chem· September 2018

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Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide.
Reatul Karim, Elise Lepeltier, Lucille Esnault, Pascal Pigeon, Laurent Lemaire

Nanoscale· July 2018

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A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties.
Yong Wang, Patrick M Dansette, Pascal Pigeon, Siden Top, Michael J McGlinchey

Chem Sci· January 2018

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A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin.
Pascal Pigeon, Yong Wang, Siden Top, Feten Najlaoui, Maria Concepcion Garcia Alvarez

J Med Chem· October 2017

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Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells.
Valeria Scalcon, Michèle Salmain, Alessandra Folda, Siden Top, Pascal Pigeon

Metallomics· July 2017

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Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro.
Valeria Scalcon, Anna Citta, Alessandra Folda, Alberto Bindoli, Michèle Salmain, Pascal Pigeon

J Inorg Biochem· December 2016

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Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation.
Yong Wang, Marie-Aude Richard, Siden Top, Patrick M Dansette, Pascal Pigeon

Angew Chem Int Ed Engl· August 2016

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The length of the bridging chain in ansa-metallocenes influences their antiproliferative activity against triple negative breast cancer cells (TNBC).
Matthieu Beauperin, Siden Top, Marie-Aude Richard, Damian Plażuk, Pascal Pigeon

Dalton Trans· August 2016

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Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites.
Nicolli Bellotti de Souza, Anna Caroline Campos Aguiar, Alane Cabral de Oliveira, Siden Top, Pascal Pigeon

Mem Inst Oswaldo Cruz· December 2015

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