Publications by authors named "Pascal Roger"

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Anti-cathepsin D antibody-drug conjugates for the targeted delivery of monomethyl auristatin F and E elicit potent anticancer activity in breast cancer.
Diane Nishimwe, Gaëlle Guillon, Aude Mallavialle, Camille Martin, Steve Huvelle, Pascal Roger

Biomed Pharmacother· December 2025

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Ovarian stromal hyperthecosis: An underestimated virilizing disorder in postmenopausal women.
Ons Boudaouara, Anis Sellami, Pascal Roger

Ann Endocrinol (Paris)· September 2025

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Cathepsins: Novel opportunities for antibody therapeutics in cancer.
Timothée David, Pénélope Desroys du Roure, Aude Mallavialle, Valérie Laurent-Matha, Pascal Roger

Br J Pharmacol· April 2025

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Antibodies against the multifaceted cathepsin D protein open new avenues for TNBC immunotherapy.
Pénélope Desroys du Roure, Timothée David, Aude Mallavialle, Valérie Laurent-Matha, Pascal Roger

J Immunother Cancer· January 2025

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Prognostic value of tertiary lymphoid structures in triple-negative breast cancer: integrated analysis with the tumor microenvironment and clinicopathological features.
Florence Boissière-Michot, Marie-Christine Chateau, Simon Thézenas, Virginie Lafont, Evelyne Crapez, Pascal Roger

Front Immunol· December 2024

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A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer.
Pénélope Desroys du Roure, Laurie Lajoie, Aude Mallavialle, Lindsay B Alcaraz, Hanane Mansouri, Pascal Roger

J Immunother Cancer· January 2024

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Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer.
Timothée David, Aude Mallavialle, Julien Faget, Lindsay B Alcaraz, Marion Lapierre, Pascal Roger

Br J Pharmacol· November 2023

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A deep-learning algorithm to localize basal cell carcinoma foci on Mohs surgery frozen sections.
Hugo Bonnefille, Marwan Abbas, Pascal Roger, François Habib, Farzaneh Masset

J Eur Acad Dermatol Venereol· May 2023

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SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity.
Lindsay B Alcaraz, Aude Mallavialle, Caroline Mollevi, Florence Boissière-Michot, Hanane Mansouri, Pascal Roger

Int J Cancer· March 2023

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Diagnostic Accuracy of Digital Staining ex vivo Confocal Microscopy for Diagnosing and Subtyping Basal Cell Carcinoma in Fresh Pretherapeutic Punch Biopsies: A Monocentric Prospective Study.
Blanche Bergeret, Farzaneh Masset, Yona D Bekoy, Pascal Roger, François Habib

Dermatology· May 2022

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Collagenase-Induced Patellar Tendinopathy with Neovascularization: First Results towards a Piglet Model of Musculoskeletal Embolization.
Julien Ghelfi, Marylène Bacle, Olivier Stephanov, Hélène de Forges, Ian Soulairol, Pascal Roger

Biomedicines· December 2021

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[2021 update of the GEFPICS' recommendations for HER2 status assessment in invasive breast cancer in France].
Camille Franchet, Lounes Djerroudi, Aurélie Maran-Gonzalez, Olivia Abramovici, Martine Antoine, Pascal Roger

Ann Pathol· November 2021

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Metachronous second primary neoplasia in oropharyngeal cancer patients: Impact of tumor HPV status. A GETTEC multicentric study.
Florent Milliet, Alexandre Bozec, Renaud Schiappa, Julien Viotti, Anouchka Modesto, Pascal Roger

Oral Oncol· November 2021

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Prognostic Impact of pT3 Subclassification in a Multicentre Cohort of Patients with Urothelial Carcinoma of the Renal Pelvicalyceal System Undergoing Radical Nephroureterectomy: A Propensity Score-weighted Analysis After Central Pathology Review.
Thomas Seisen, Andrea Mari, Riccardo Campi, Benoit Peyronnet, Karim Bensalah, Pascal Roger

Eur Urol Focus· September 2021

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A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment.
Lindsay B Alcaraz, Aude Mallavialle, Timothée David, Danielle Derocq, Frédéric Delolme, Pascal Roger

Theranostics· July 2021

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Upfront surgery or definitive radiotherapy for p16+ oropharyngeal cancer. A GETTEC multicentric study.
Dorian Culié, Renaud Schiappa, Anouchka Modesto, Julien Viotti, Emmanuel Chamorey, Pascal Roger

Eur J Surg Oncol· June 2021

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Upfront surgery or definitive radiotherapy for patients with p16-negative oropharyngeal squamous cell carcinoma. A GETTEC multicentric study.
Dorian Culié, Julien Viotti, Anouchka Modesto, Renaud Schiappa, Emmanuel Chamorey, Pascal Roger

Eur J Surg Oncol· February 2021

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Synchronous primary neoplasia in patients with oropharyngeal cancer: Impact of tumor HPV status. A GETTEC multicentric study.
Florent Milliet, Alexandre Bozec, Renaud Schiappa, Julien Viotti, Anouchka Modesto, Pascal Roger

Oral Oncol· January 2021

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Oropharyngeal cancer: First relapse description and prognostic factor of salvage treatment according to p16 status, a GETTEC multicentric study.
Dorian Culié, Quentin Lisan, Charlotte Leroy, Anouchka Modesto, Renaud Schiappa, Pascal Roger

Eur J Cancer· January 2021

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Characterisation of tumour microenvironment and immune checkpoints in primary central nervous system diffuse large B cell lymphomas.
Melissa Alame, Marion Pirel, Valérie Costes-Martineau, Luc Bauchet, Michel Fabbro, Pascal Roger

Virchows Arch· June 2020

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Co-Expression of Androgen Receptor and Cathepsin D Defines a Triple-Negative Breast Cancer Subgroup with Poorer Overall Survival.
Hanane Mansouri, Lindsay B Alcaraz, Caroline Mollevi, Aude Mallavialle, William Jacot, Pascal Roger

Cancers (Basel)· May 2020

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[GEFPICS' guidelines for management of breast cancer tissue samples in the neoadjuvant setting].
Aurélie Maran-Gonzalez, Camille Franchet, Raphaëlle Duprez-Paumier, Martine Antoine, Catherine Barlier, Pascal Roger

Ann Pathol· December 2019

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Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies.
Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B Alcaraz, Pascal Roger

J Immunother Cancer· February 2019

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Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
Alexandre T J Maria, Karine Toupet, Claire Bony, Nelly Pirot, Marie-Catherine Vozenin, Pascal Roger

Arthritis Rheumatol· April 2016

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Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
Anne-Sophie Bach, Danielle Derocq, Valérie Laurent-Matha, Philippe Montcourrier, Salwa Sebti, Pascal Roger

Oncotarget· September 2015

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