Publications by authors named "Pascal Zihlmann"

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Strengthening an Intramolecular Non-Classical Hydrogen Bond to Get in Shape for Binding.
Norbert Varga, Martin Smieško, Xiaohua Jiang, Roman P Jakob, Beatrice Wagner, Pascal Zihlmann

Angew Chem Int Ed Engl· October 2024

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Enhancing the enthalpic contribution of hydrogen bonds by solvent shielding.
Jonathan Cramer, Xiaohua Jiang, Wojciech Schönemann, Marleen Silbermann, Pascal Zihlmann

RSC Chem Biol· October 2020

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Improvement of Aglycone π-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists.
Wojciech Schönemann, Jonathan Cramer, Tobias Mühlethaler, Brigitte Fiege, Marleen Silbermann, Pascal Zihlmann

ChemMedChem· April 2019

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KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.
Pascal Zihlmann, Marleen Silbermann, Timothy Sharpe, Xiaohua Jiang, Tobias Mühlethaler

Chemistry· September 2018

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The price of flexibility - a case study on septanoses as pyranose mimetics.
Christoph P Sager, Brigitte Fiege, Pascal Zihlmann, Raghu Vannam, Said Rabbani

Chem Sci· January 2018

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Carbohydrate-Lectin Interactions: An Unexpected Contribution to Affinity.
Giulio Navarra, Pascal Zihlmann, Roman P Jakob, Katja Stangier, Roland C Preston

Chembiochem· March 2017

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Mutation of Tyr137 of the universal fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
Said Rabbani, Eva-Maria Krammer, Goedele Roos, Adam Zalewski, Roland Preston, Pascal Zihlmann

IUCrJ· January 2017

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The tyrosine gate of the bacterial lectin FimH: a conformational analysis by NMR spectroscopy and X-ray crystallography.
Brigitte Fiege, Said Rabbani, Roland C Preston, Roman P Jakob, Pascal Zihlmann

Chembiochem· May 2015

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FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile.
Simon Kleeb, Lijuan Pang, Katharina Mayer, Deniz Eris, Anja Sigl, Pascal Zihlmann

J Med Chem· March 2015

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