Publications by authors named "Patricio Manque"

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Comprehensive molecular analysis of early‑onset gastric cancer identifies novel genes implicated in disease characterization and progression (Review).
Fernán Gómez-Valenzuela, Ian Silva, Ignacio N Retamal, Benjamín García-Bloj, Tomás De Mayo Glasser, Patricio A Manque

Oncol Rep· August 2025

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A germline variant of ring finger protein 43 in an early onset, treatment-resistant metastatic gastric cancer: a case report.
Benjamín García-Bloj, Santiago Farah Celis, Natalia Eva Orellana, Tomás de Mayo Glasser, Mauricio A Sáez, Patricio A Manque

J Gastrointest Oncol· August 2025

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Isocitrate dehydrogenase 1 gene mutations: a case review unveiling its biological impact on disease progression, prognosis and treatment in Chilean patients.
Tomás de Mayo Glasser, Benjamín García-Bloj, Juan A Godoy, Fernando Sigler Chávez, Ignacio N Retamal, Patricio A Manque

BJR Case Rep· March 2025

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The autophagy protein RUBCNL/PACER represses RIPK1 kinase-dependent apoptosis and necroptosis.
Diego Rojas-Rivera, Sebastián Beltrán, Francisco Muñoz-Carvajal, Pablo Ahumada-Montalva, Lorena Abarzúa, Patricio A Manque

Autophagy· November 2024

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Overexpression of autophagy enhancer PACER/RUBCNL in neurons accelerates disease in the SOD1 ALS mouse model.
Luis Labrador, Leonardo Rodriguez, Sebastián Beltran, Fernanda Hernandez, Laura Gomez, Patricio Manque

Biol Res· November 2024

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, a bridge between oral health and immune evasion in gastric cancer.
Matías Muñoz-Medel, Mauricio P Pinto, Lauren Goralsky, Mónica Cáceres, Franz Villarroel-Espíndola, Patricio Manque

Front Oncol· May 2024

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Proteogenomic analysis in an early onset diffuse gastric cancer patient revealed alterations in PIK3R1, TP53, SMAD4 and a potential role of the PI3K-AKT and EGFR pathways: a case report.
Miguel Cordova-Delgado, Mauricio P Pinto, Gonzalo Pizarro, Elard Koch, Cristian Vargas, Patricio Manque

J Gastrointest Oncol· August 2022

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Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease.
Sandra Espinoza, Felipe Grunenwald, Wileidy Gomez, Felipe García, Lorena Abarzúa-Catalan, Patricio A Manque

Cells· June 2022

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The Autophagy Protein Pacer Positively Regulates the Therapeutic Potential of Mesenchymal Stem Cells in a Mouse Model of DSS-Induced Colitis.
Cristian A Bergmann, Sebastian Beltran, Ana Maria Vega-Letter, Paola Murgas, Maria Fernanda Hernandez, Patricio A Manque

Cells· April 2022

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Mutational Landscape and Actionable Target Rates on Advanced Stage Refractory Cancer Patients: A Multicenter Chilean Experience.
Miguel Cordova-Delgado, Mauricio P Pinto, Carlos Regonesi, Luis Cereceda, José Miguel Reyes, Patricio Manque

J Pers Med· January 2022

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DEF8 and Autophagy-Associated Genes Are Altered in Mild Cognitive Impairment, Probable Alzheimer's Disease Patients, and a Transgenic Model of the Disease.
Esteban Leyton, Diego Matus, Sandra Espinoza, José Matías Benitez, Bastián I Cortés, Patricio Manque

J Alzheimers Dis· September 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Patricio Manque

Autophagy· January 2021

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Decoding Gene Networks Modules That Explain the Recovery of Cav. After Extreme Desiccation.
Enrique Ostria-Gallardo, Giovanni Larama, Graciela Berríos, Ana Fallard, Ana Gutiérrez-Moraga, Patricio Manque

Front Plant Sci· May 2020

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Implications of Selective Autophagy Dysfunction for ALS Pathology.
Emiliano Vicencio, Sebastián Beltrán, Luis Labrador, Patricio Manque, Melissa Nassif

Cells· February 2020

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Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs.
Cristian De Gregorio, Paula Díaz, Rodrigo López-Leal, Patricio Manque, Felipe A Court

Methods Mol Biol· January 2019

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Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.
José Manuel Matamala, Raul Arias-Carrasco, Carolina Sanchez, Markus Uhrig, Leslie Bargsted, Patricio Manque

Neurobiol Aging· April 2018

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Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.
Natalia Salvadores, Mario Sanhueza, Patricio Manque, Felipe A Court

Front Neurosci· September 2017

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The Enigmatic Role of C9ORF72 in Autophagy.
Melissa Nassif, Ute Woehlbier, Patricio A Manque

Front Neurosci· August 2017

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High quality RNA extraction from Maqui berry for its application in next-generation sequencing.
Carolina Sánchez, Javier Villacreses, Noelle Blanc, Loreto Espinoza, Camila Martinez, Patricio Manque

Springerplus· August 2016

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Revisiting the reference genomes of human pathogenic Cryptosporidium species: reannotation of C. parvum Iowa and a new C. hominis reference.
Juan P Isaza, Ana Luz Galván, Victor Polanco, Bernice Huang, Andrey V Matveyev, Patricio Manque

Sci Rep· November 2015

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Deep sequencing reveals the complete genome and evidence for transcriptional activity of the first virus-like sequences identified in Aristotelia chilensis (Maqui Berry).
Javier Villacreses, Marcelo Rojas-Herrera, Carolina Sánchez, Nicole Hewstone, Soledad F Undurraga, Patricio Manque

Viruses· April 2015

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The effect of tunicamycin on the glucose uptake, growth, and cellular adhesion in the protozoan parasite Crithidia fasciculata.
Robert Rojas, Christopher Segovia, Annette Nicole Trombert, Javier Santander, Patricio Manque

Curr Microbiol· October 2014

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Draft Genome Sequence of Virulent Strain AUSTRAL-005 of Piscirickettsia salmonis, the Etiological Agent of Piscirickettsiosis.
Alejandro J Yañez, Cristian Molina, Ronie E Haro, Patricio Sanchez, Adolfo Isla, Patricio Manque

Genome Announc· October 2014

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Intranasal vaccination in mice with an attenuated Salmonella enterica Serovar 908htr A expressing Cp15 of Cryptosporidium: impact of malnutrition with preservation of cytokine secretion.
James K Roche, Ana Lara Rojo, Lourrany B Costa, Ronald Smeltz, Patricio Manque

Vaccine· January 2013

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Identification and characterization of a novel calcium-activated apyrase from Cryptosporidium parasites and its potential role in pathogenesis.
Patricio A Manque, Ute Woehlbier, Ana M Lara, Fernando Tenjo, João M Alves

PLoS One· June 2012

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