Publications by authors named "Patrick C Mahon"

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Corrigendum: FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity.
Patrick C Mahon, Kiichi Hirota, Gregg L Semenza

Genes Dev· July 2025

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Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.
Paul A Brough, Lisa Baker, Simon Bedford, Kirsten Brown, Seema Chavda, Patrick C Mahon

J Med Chem· March 2017

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VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells.
Jonathan D Moore, Anna Staniszewska, Terence Shaw, Jalanie D'Alessandro, Ben Davis, Patrick C Mahon

Oncotarget· December 2014

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S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer.
Patrick C Mahon, Patrick Baril, Vipul Bhakta, Claude Chelala, Krishna Caulee

Cancer Res· July 2007

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Jin Hyen Baek, Patrick C Mahon, Jane Oh, Brian Kelly, Balaji Krishnamachary

Mol Cell· February 2005

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