Publications by authors named "Patrick Cramer"

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Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis.
Florian Kabinger, Carina Stiller, Jana Schmitzová, Christian Dienemann, Goran Kokic, Hauke S Hillen, Claudia Höbartner, Patrick Cramer

Nat Struct Mol Biol· September 2021

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Molecular mechanism of co-transcriptional H3K36 methylation by SETD2.
James L Walshe, Moritz Ochmann, Ute Neef, Olexandr Dybkov, Christian Dienemann, Patrick Cramer

Nat Commun· October 2025

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Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.
Luisa M Welp, Alexander Wulf, Aleksandar Chernev, Yehor Horokhovskyi, Sergei Moshkovskii, Patrick Cramer

Nucleic Acids Res· August 2025

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IWS1 positions downstream DNA to globally stimulate Pol II elongation.
Aiturgan Zheenbekova, James L Walshe, Moritz Ochmann, Moritz Bäuerle, Ute Neef, Patrick Cramer

Nat Commun· August 2025

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Structure of a transcribing Pol II-DSIF-SPT6-U1 snRNP complex.
Luojia Zhang, Christopher Batters, Shintaro Aibara, Yuliya Gordiyenko, Kristina Žumer, Patrick Cramer

Nat Commun· July 2025

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Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition.
Kseniia Lysakovskaia, Arjun Devadas, Björn Schwalb, Michael Lidschreiber, Patrick Cramer

Nat Struct Mol Biol· June 2025

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Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.
Luisa M Welp, Alexander Wulf, Aleksandar Chernev, Yehor Horokhovskyi, Sergei Moshkovskii, Patrick Cramer

bioRxiv· May 2025

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Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr.
Florian Kabinger, Valerie Doze, Jana Schmitzová, Michael Lidschreiber, Christian Dienemann, Patrick Cramer

Proc Natl Acad Sci U S A· March 2025

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Publisher Correction: Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition.
Kseniia Lysakovskaia, Arjun Devadas, Björn Schwalb, Michael Lidschreiber, Patrick Cramer

Nat Struct Mol Biol· March 2025

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Mechanism of polyadenylation-independent RNA polymerase II termination.
Srinivasan Rengachari, Thomas Hainthaler, Christiane Oberthuer, Michael Lidschreiber, Patrick Cramer

Nat Struct Mol Biol· February 2025

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STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair.
Diana van den Heuvel, Marta Rodríguez-Martínez, Paula J van der Meer, Nicolas Nieto Moreno, Jiyoung Park, Patrick Cramer

Cell· December 2024

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Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Maik Engeholm, Johann J Roske, Elisa Oberbeckmann, Christian Dienemann, Michael Lidschreiber, Patrick Cramer

Mol Cell· September 2024

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The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.
Sohan Patil, Gregor Cremosnik, Lara Dötsch, Jana Flegel, Britta Schulte, Patrick Cramer

Angew Chem Int Ed Engl· August 2024

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STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair.
Diana van den Heuvel, Marta Rodríguez-Martínez, Paula J van der Meer, Nicolas Nieto Moreno, Jiyoung Park, Patrick Cramer

bioRxiv· July 2024

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FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo.
Kristina Žumer, Moritz Ochmann, Abrar Aljahani, Aiturgan Zheenbekova, Arjun Devadas, Patrick Cramer

Mol Cell· June 2024

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CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release.
Taras Velychko, Eusra Mohammad, Ivan Ferrer-Vicens, Iwan Parfentev, Marcel Werner, Patrick Cramer

Mol Cell· June 2024

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Structural basis of Integrator-dependent RNA polymerase II termination.
Isaac Fianu, Moritz Ochmann, James L Walshe, Olexandr Dybkov, Joseph Neos Cruz, Patrick Cramer

Nature· May 2024

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Three-step mechanism of promoter escape by RNA polymerase II.
Yumeng Zhan, Frauke Grabbe, Elisa Oberbeckmann, Christian Dienemann, Patrick Cramer

Mol Cell· May 2024

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In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization.
Elisa Oberbeckmann, Kimberly Quililan, Patrick Cramer, A Marieke Oudelaar

Nat Genet· March 2024

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Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
Goran Kokic, George Yakoub, Diana van den Heuvel, Annelotte P Wondergem, Paula J van der Meer, Patrick Cramer

Nat Struct Mol Biol· March 2024

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Good reasons for structural biology.
Patrick Cramer

Nat Struct Mol Biol· March 2024

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RNA polymerase II elongation factors use conserved regulatory mechanisms.
Ying Chen, Patrick Cramer

Curr Opin Struct Biol· February 2024

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Structure of the transcribing RNA polymerase II-Elongin complex.
Ying Chen, Goran Kokic, Christian Dienemann, Olexandr Dybkov, Henning Urlaub, Patrick Cramer

Nat Struct Mol Biol· December 2023

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MSL2 ensures biallelic gene expression in mammals.
Yidan Sun, Meike Wiese, Raed Hmadi, Remzi Karayol, Janine Seyfferth, Patrick Cramer

Nature· December 2023

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Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.
Anna Palau, Filip Segerberg, Michael Lidschreiber, Katja Lidschreiber, Aonghus J Naughton, Patrick Cramer

Leukemia· September 2023

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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II.
David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Patrick Cramer

Nat Commun· September 2023

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