Publications by authors named "Patrick Descombes"

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Developing a core collection for the conservation of Theobroma cacao's genetic diversity.
Evelyn T Todd, Fabrizio Arigoni, James A Holzwarth, Laurence Bellanger, Patrick Descombes

BMC Genomics· October 2025

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The genome and population genomics of allopolyploid Coffea arabica reveal the diversification history of modern coffee cultivars.
Jarkko Salojärvi, Aditi Rambani, Zhe Yu, Romain Guyot, Susan Strickler, Patrick Descombes

Nat Genet· April 2024

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Adipose tissue angiogenesis genes are down-regulated by grape polyphenols supplementation during a human overfeeding trial.
Pauline Delage, Bérénice Ségrestin, Kévin Seyssel, Stéphanie Chanon, Aurélie Vieille-Marchiset, Patrick Descombes

J Nutr Biochem· July 2023

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Global transcriptome profiling reveals differential regulatory, metabolic and hormonal networks during somatic embryogenesis in Coffea arabica.
Rayan Awada, Maud Lepelley, David Breton, Aline Charpagne, Claudine Campa, Patrick Descombes

BMC Genomics· January 2023

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Ecological and genomic vulnerability to climate change across native populations of Robusta coffee (Coffea canephora).
Rémi Tournebize, Leyli Borner, Stéphanie Manel, Christine N Meynard, Yves Vigouroux, Patrick Descombes

Glob Chang Biol· July 2022

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Mitochondrial respiratory chain dysfunction alters ER sterol sensing and mevalonate pathway activity.
Christopher Tadhg James Wall, Gregory Lefebvre, Sylviane Metairon, Patrick Descombes, Andreas Wiederkehr

J Biol Chem· March 2022

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In vivo transcriptomic profiling using cell encapsulation identifies effector pathways of systemic aging.
Omid Mashinchian, Xiaotong Hong, Joris Michaud, Eugenia Migliavacca, Gregory Lefebvre, Patrick Descombes

Elife· March 2022

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Longitudinal Human Milk miRNA Composition over the First 3 mo of Lactation in a Cohort of Healthy Mothers Delivering Term Infants.
Frederic Raymond, Gregory Lefebvre, Lorane Texari, Solenn Pruvost, Sylviane Metairon, Patrick Descombes

J Nutr· January 2022

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Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.
Philipp Rhein, Eric M Desjardins, Ping Rong, Danial Ahwazi, Nicolas Bonhoure, Patrick Descombes

Mol Metab· September 2021

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Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents.
Carlos Alessandro Fuzo, Fábio da Veiga Ued, Sofia Moco, Ornella Cominetti, Sylviane Métairon, Patrick Descombes

Sci Rep· June 2021

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Whole-genome sequencing analysis of semi-supercentenarians.
Paolo Garagnani, Julien Marquis, Massimo Delledonne, Chiara Pirazzini, Elena Marasco, Patrick Descombes

Elife· May 2021

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The absence of the caffeine synthase gene is involved in the naturally decaffeinated status of Coffea humblotiana, a wild species from Comoro archipelago.
Nathalie Raharimalala, Stephane Rombauts, Andrew McCarthy, Andréa Garavito, Simon Orozco-Arias, Patrick Descombes

Sci Rep· April 2021

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DNA methylation during human adipogenesis and the impact of fructose.
Giulia Tini, Vijayalakshmi Varma, Rosario Lombardo, Greg T Nolen, Gregory Lefebvre, Patrick Descombes

Genes Nutr· November 2020

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Complex evolutionary history of coffees revealed by full plastid genomes and 28,800 nuclear SNP analyses, with particular emphasis on Coffea canephora (Robusta coffee).
Jean-Claude Charr, Andrea Garavito, Christophe Guyeux, Dominique Crouzillat, Patrick Descombes

Mol Phylogenet Evol· October 2020

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Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans.
Marco Sazzini, Paolo Abondio, Stefania Sarno, Guido Alberto Gnecchi-Ruscone, Matteo Ragno, Patrick Descombes

BMC Biol· May 2020

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Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics.
Bernard Berger, Nadine Porta, Francis Foata, Dominik Grathwohl, Michèle Delley, Patrick Descombes

mBio· March 2020

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Mitochondrial oxidative capacity and NAD biosynthesis are reduced in human sarcopenia across ethnicities.
Eugenia Migliavacca, Stacey K H Tay, Harnish P Patel, Tanja Sonntag, Gabriele Civiletto, Patrick Descombes

Nat Commun· December 2019

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AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
Caterina Collodet, Marc Foretz, Maria Deak, Laurent Bultot, Sylviane Metairon, Patrick Descombes

FASEB J· November 2019

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Persistent low body weight in humans is associated with higher mitochondrial activity in white adipose tissue.
Yiin Ling, Jérôme Carayol, Bogdan Galusca, Carles Canto, Christophe Montaurier, Patrick Descombes

Am J Clin Nutr· September 2019

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Development and evaluation of a genome-wide Coffee 8.5K SNP array and its application for high-density genetic mapping and for investigating the origin of Coffea arabica L.
Virginie Merot-L'anthoene, Rémi Tournebize, Olivier Darracq, Vimel Rattina, Maud Lepelley, Patrick Descombes

Plant Biotechnol J· July 2019

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Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice.
Corinne Haller, Julie Piccand, Filippo De Franceschi, Yuki Ohi, Anindita Bhoumik, Patrick Descombes

Stem Cell Reports· April 2019

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Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.
Armand Valsesia, Sameer S Kulkarni, Julien Marquis, Patricia Leone, Polina Mironova, Patrick Descombes

Am J Clin Nutr· April 2019

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Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
Laura Lukjanenko, Sonia Karaz, Pascal Stuelsatz, Uxia Gurriaran-Rodriguez, Joris Michaud, Patrick Descombes

Cell Stem Cell· March 2019

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Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.
Armand Valsesia, Qiao-Ping Wang, Nele Gheldof, Jérôme Carayol, Hélène Ruffieux, Patrick Descombes

Nat Commun· February 2019

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Bangladeshi children with acute diarrhoea show faecal microbiomes with increased Streptococcus abundance, irrespective of diarrhoea aetiology.
Silas Kieser, Shafiqul A Sarker, Olga Sakwinska, Francis Foata, Shamima Sultana, Patrick Descombes

Environ Microbiol· June 2018

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