Publications by authors named "Patrick Eden"

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Discovery of N-(4-(3-(2-aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), a highly selective, orally bioavailable inhibitor of aurora kinases with activity against multidrug-resistant cancer cell lines.
Stephanie Geuns-Meyer, Victor J Cee, Holly L Deak, Bingfan Du, Brian L Hodous, Patrick Eden

J Med Chem· July 2015

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Preclinical evaluation of AMG 900, a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines.
Marc Payton, Tammy L Bush, Grace Chung, Beth Ziegler, Patrick Eden

Cancer Res· December 2010

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Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
Victor J Cee, Laurie B Schenkel, Brian L Hodous, Holly L Deak, Hanh N Nguyen, Patrick M Eden

J Med Chem· September 2010

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