Publications by authors named "Patrick Ehm"

Claim this Profile
T
The Inositol-5-Phosphatase SHIP1: Expression, Regulation and Role in Acute Lymphoblastic Leukemia.
Patrick Ehm, Manfred Jücker

Int J Mol Sci· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway.
Patrick A H Ehm, Stefan Horn, Konstantin Hoffer, Malte Kriegs, Michael Horn

Cell Commun Signal· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases.
Patrick A H Ehm, Michael Linnebacher, Andreas Block, Christoph Rehbach, Manfred Jücker

Cell Signal· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model.
Patrick Ehm, Ruth Rietow, Wiebke Wegner, Lara Bußmann, Malte Kriegs

Cells· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021.
Patrick Ehm, Bettina Bettin, Manfred Jücker

Biochim Biophys Acta Mol Cell Res· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants.
Patrick Ehm, Nina Nelson, Susanne Giehler, Matthias Schaks, Bettina Bettin

Cell Signal· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
J
JAK2-V617F is a negative regulation factor of SHIP1 protein and thus influences the AKT signaling pathway in patients with Myeloproliferative neoplasm (MPN).
Madeleine Glück, Lina Dally, Manfred Jücker, Patrick Ehm

Int J Biochem Cell Biol· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL).
Patrick Ehm, Astrid Grottke, Bettina Bettin, Manfred Jücker

Cell Signal· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids : A 3D Tumour Model for Pre-therapeutic Drug Screening.
Dominik Nörz, Christina S Mullins, Daniel J Smit, Michael Linnebacher, Grith Hagel, Patrick Ehm

Anticancer Res· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Ectopic Expression of Hematopoietic SHIP1 in Human Colorectal Cancer.
Matthias Schaks, Kristina Allgoewer, Nina Nelson, Patrick Ehm, Asmus Heumann

Biomedicines· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins.
Patrick A H Ehm, Fabiola Lange, Carolin Hentschel, Anneke Jepsen, Madeleine Glück

Cell Signal· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nuclear accumulation of SHIP1 mutants derived from AML patients leads to increased proliferation of leukemic cells.
Marcus M Nalaskowski, Patrick Ehm, Christoph Rehbach, Nina Nelson, Maike Täger

Cell Signal· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies.
Patrick Ehm, Marcus M Nalaskowski, Torsten Wundenberg, Manfred Jücker

Nucleus· January 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
Jasmin Wellbrock, Emily Latuske, Julian Köhler, Katharina Wagner, Hauke Stamm, Patrick Ehm

Clin Cancer Res· May 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase.
Inga Kublun, Patrick Ehm, Maria A Brehm, Marcus M Nalaskowski

Biochimie· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A toolkit for graded expression of green fluorescent protein fusion proteins in mammalian cells.
Marcus M Nalaskowski, Patrick Ehm, Susanne Giehler, Georg W Mayr

Anal Biochem· September 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nucleocytoplasmic shuttling of human inositol phosphate multikinase is influenced by CK2 phosphorylation.
Rüdiger Meyer, Marcus M Nalaskowski, Patrick Ehm, Constantin Schröder, Xenia Naj, Maria A Brehm

Biol Chem· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis