Publications by authors named "Patrick Hanafin"

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Population Pharmacokinetic/Toxicodynamic Model for Polymyxin B in Critically Ill Patients to Identify the Risk of Nephrotoxicity.
Patrick O Hanafin, Ramya Mahadevan, Gauri G Rao, Alexandre P Zavascki, Ana Maria Sandri

Clin Pharmacol Ther· October 2025

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Belantamab Mafodotin with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: A Comprehensive Exposure-Response Analysis of the DREAMM-8 Study.
Patrick Hanafin, Yu Liu Ho, Theodoros Papathanasiou, Giulia Fulci, Neal Sule

Target Oncol· September 2025

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A population pharmacokinetic model of polymyxin B based on prospective clinical data to inform dosing in hospitalized patients.
Patrick O Hanafin, Andrea Kwa, Alexandre P Zavascki, Ana Maria Sandri, Marc H Scheetz

Clin Microbiol Infect· September 2023

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Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations.
Shekhar B Yeshwante, Patrick Hanafin, Brittany K Miller, Laura Rank, Sebastian Murcia

Mol Pharm· September 2023

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International society of Pharmacometrics Mentorship Program (IMP): feedback survey from the first cohort of mentor-mentee pairs.
Patrick O Hanafin, Ananya Murthy, Dhananjay Marathe, John K Diep, Anu Shilpa Krishnatry

J Pharmacokinet Pharmacodyn· August 2023

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Pharmacokinetic considerations for optimizing inhaled spray-dried pyrazinoic acid formulations.
Shekhar B Yeshwante, Patrick Hanafin, Brittany K Miller, Laura Rank, Sebastian Murcia

bioRxiv· April 2023

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Proof-of-concept for incorporating mechanistic insights from multi-omics analyses of polymyxin B in combination with chloramphenicol against Klebsiella pneumoniae.
Patrick O Hanafin, Nusaibah Abdul Rahim, Rajnikant Sharma, Colin G Cess, Stacey D Finley

CPT Pharmacometrics Syst Pharmacol· March 2023

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A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections.
Courtney L Luterbach, Hongqiang Qiu, Patrick O Hanafin, Rajnikant Sharma, Joseph Piscitelli

Antimicrob Agents Chemother· October 2022

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Co-worker relationships and their impact on nurses in Irish public healthcare settings.
Sinéad Hanafin, Jude Cosgrove, Patrick Hanafin, Ciaran Lynch, Anne-Marie Brady

Br J Nurs· April 2022

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Assessing the predictive performance of population pharmacokinetic models for intravenous polymyxin B in critically ill patients.
Patrick O Hanafin, Roger L Nation, Marc H Scheetz, Alexandre P Zavascki, Ana M Sandri

CPT Pharmacometrics Syst Pharmacol· December 2021

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Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis.
Patrick O Hanafin, Isabelle Sermet-Gaudelus, Matthias Griese, Matthias Kappler, Helmut Ellemunter

Front Pharmacol· August 2021

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Reapproaching Old Treatments: Considerations for PK/PD Studies on Phage Therapy for Bacterial Respiratory Infections.
Alan A Schmalstig, Soha Freidy, Patrick O Hanafin, Miriam Braunstein, Gauri G Rao

Clin Pharmacol Ther· June 2021

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Evaluation Strategies for Triple-Drug Combinations against Carbapenemase-Producing Klebsiella Pneumoniae in an In Vitro Hollow-Fiber Infection Model.
Estefany Garcia, John K Diep, Rajnikant Sharma, Patrick O Hanafin, Cely S Abboud

Clin Pharmacol Ther· April 2021

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A mechanism-based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID-19 treatment in humans.
Patrick O Hanafin, Brian Jermain, Anthony J Hickey, Alexander V Kabanov, Angela Dm Kashuba

CPT Pharmacometrics Syst Pharmacol· February 2021

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Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing.
Brian Jermain, Patrick O Hanafin, Yanguang Cao, Adrian Lifschitz, Carlos Lanusse

J Pharm Sci· December 2020

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Burnout and its prevalence among public health nurses in Ireland.
Sinead Hanafin, Jude Cosgrove, Patrick Hanafin, Anne-Marie Brady, Ciaran Lynch

Br J Community Nurs· August 2020

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Influence of Renal Function on Evolocumab Exposure, Pharmacodynamics, and Safety.
Edward Lee, John P Gibbs, Maurice G Emery, Geoffrey Block, Scott M Wasserman, Patrick Hanafin

Clin Pharmacol Drug Dev· April 2019

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Reproductive rights and the Irish Constitution: from the sanctity of life to the sanctity of autonomy?
Patrick Hanafin

Eur J Health Law· June 1996

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