Publications by authors named "Patrick Heizer"

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Differential regulation of Treg stability in human naïve and effector Treg subsets by TGFβ-signaling via ARKADIA-SKI axis.
Fan Yang, Alexis Yanes, Miao Li, Patrick Heizer, Ivan Linatoc

Front Immunol· September 2025

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The accumulation of progerin underlies the loss of aortic smooth muscle cells in Hutchinson-Gilford progeria syndrome.
Paul H Kim, Joonyoung R Kim, Patrick J Heizer, Hyesoo Jung, Yiping Tu

Cell Death Dis· July 2025

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The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome.
Paul H Kim, Joonyoung R Kim, Patrick J Heizer, Hyesoo Jung, Yiping Tu

bioRxiv· November 2024

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AAV-mediated co-expression of an immunogenic transgene plus PD-L1 enables sustained expression through immunological evasion.
Travis B McMurphy, Andrew Park, Patrick J Heizer, Crystal Bottenfield, James H Kurasawa

Sci Rep· November 2024

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Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures.
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston

Proc Natl Acad Sci U S A· February 2023

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Nuclear membrane ruptures underlie the vascular pathology in a mouse model of Hutchinson-Gilford progeria syndrome.
Paul H Kim, Natalie Y Chen, Patrick J Heizer, Yiping Tu, Thomas A Weston

JCI Insight· August 2021

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Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts.
Natalie Y Chen, Paul H Kim, Yiping Tu, Ye Yang, Patrick J Heizer

Proc Natl Acad Sci U S A· June 2021

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Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins.
Cuiwen He, Haibo Jiang, Wenxin Song, Howard Riezman, Peter Tontonoz, Patrick Heizer

Proc Natl Acad Sci U S A· May 2020

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Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores.
Patrick J Heizer, Ye Yang, Yiping Tu, Paul H Kim, Natalie Y Chen

J Lipid Res· March 2020

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An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death.
Natalie Y Chen, Ye Yang, Thomas A Weston, Jason N Belling, Patrick Heizer

Proc Natl Acad Sci U S A· December 2019

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Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia.
Xuchen Hu, Thomas A Weston, Cuiwen He, Rachel S Jung, Patrick J Heizer

Elife· September 2019

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GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Xuchen Hu, Ken Matsumoto, Rachel S Jung, Thomas A Weston, Patrick J Heizer

Elife· June 2019

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An upstream enhancer regulates expression in a tissue-specific manner.
Christopher M Allan, Patrick J Heizer, Yiping Tu, Norma P Sandoval, Rachel S Jung

J Lipid Res· April 2019

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Lipoprotein lipase is active as a monomer.
Anne P Beigneux, Christopher M Allan, Norma P Sandoval, Geoffrey W Cho, Patrick J Heizer

Proc Natl Acad Sci U S A· March 2019

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NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.
Cuiwen He, Xuchen Hu, Thomas A Weston, Rachel S Jung, Patrick Heizer

Biochem Biophys Res Commun· October 2018

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Macrophages release plasma membrane-derived particles rich in accessible cholesterol.
Cuiwen He, Xuchen Hu, Thomas A Weston, Rachel S Jung, Jaspreet Sandhu, Patrick Heizer

Proc Natl Acad Sci U S A· September 2018

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Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome.
Paul H Kim, Jennings Luu, Patrick Heizer, Yiping Tu, Thomas A Weston

Sci Transl Med· September 2018

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NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes.
Cuiwen He, Thomas A Weston, Rachel S Jung, Patrick Heizer, Mikael Larsson

Cell Metab· May 2018

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Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure.
Mikael Larsson, Christopher M Allan, Patrick J Heizer, Yiping Tu, Norma P Sandoval

J Lipid Res· April 2018

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Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice.
Christopher M Allan, Patrick J Heizer, Cris J Jung, Yiping Tu, Deanna Tran

J Dermatol Sci· January 2018

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A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency.
Christopher M Allan, Deanna Tran, Yiping Tu, Patrick J Heizer, Lorraine C Young

Exp Dermatol· November 2017

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Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.
Mikael Larsson, Christopher M Allan, Rachel S Jung, Patrick J Heizer, Anne P Beigneux

J Lipid Res· September 2017

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Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.
Christopher M Allan, Cris J Jung, Mikael Larsson, Patrick J Heizer, Yiping Tu

J Lipid Res· July 2017

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