Publications by authors named "Patrick Kehoe"

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Dissecting the effect of long-term exposure to air pollution on risk of dementia in UK Biobank.
Ensor Rafael Palacios, Chin Yang Shapland, Levi John Wolf, Liv Tybjærg Nordestgaard, Emma Anderson, Patrick Gavin Kehoe

Environ Health· December 2025

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Elevated Na/K Ratio in Alzheimer's Disease: A Potential Biomarker for Braak Stage.
Yuma Mizuno, Shiyue Pan, Tong Zhou, Patrick G Kehoe, Yumei Feng Earley

bioRxiv· November 2025

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Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease.
Frank Jessen, Javier Arbizu, Mercé Boada, Mircea Balasa, Karim Bennys, Patrick G Kehoe

J Prev Alzheimers Dis· September 2025

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Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations.
Aude Nicolas, Richard Sherva, Benjamin Grenier-Boley, Yoontae Kim, Masataka Kikuchi, Patrick G Kehoe

Nat Genet· July 2025

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Machine learning in Alzheimer's disease genetics.
Matthew Bracher-Smith, Federico Melograna, Brittany Ulm, Céline Bellenguez, Benjamin Grenier-Boley, Patrick Kehoe

Nat Commun· July 2025

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Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer's Disease in European Populations: Development and Validation.
Bayram Cevdet Akdeniz, Shahram Bahrami, Espen Hagen, Julian Fuhrer, Vera Fominykh, Patrick Gavin Kehoe

medRxiv· July 2025

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X-chromosome-wide association study for Alzheimer's disease.
Julie Le Borgne, Lissette Gomez, Sami Heikkinen, Najaf Amin, Shahzad Ahmad, Patrick Gavin Kehoe

Mol Psychiatry· June 2025

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stratified genome-wide association studies provide novel insights into the genetic etiology of Alzheimers's disease.
Jesper Qvist Thomassen, Leonard Hampton, Brittany Ulms, Benjamin Grenier-Boley, Sami Heikkinen, Patrick Gavin Kehoe

medRxiv· May 2025

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The Contribution of the Renin-Angiotensin System to Alzheimer's Disease.
Özge Güzel, Patrick G Kehoe

Curr Top Behav Neurosci· April 2025

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Epigenetic and Metabolic Landscape of Dementia with Lewy Bodies.
Sangeetha Vishweswaraiah, Ali Yilmaz, Juozas Gordevicius, Milda Milčiūtė, Karolis Krinickis, Patrick G Kehoe

Mov Disord· March 2025

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Curious Dichotomies of Apolipoprotein E Function in Alzheimer's Disease and Cancer-One Explanatory Mechanism of Inverse Disease Associations?
Claire M Perks, Rachel M Barker, Mai Alhadrami, Omar Alkahtani, Emily Gill, Patrick G Kehoe

Genes (Basel)· March 2025

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Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Experience from the RADAR study.
Lina Jarutyte, Jan Petr, Nicholas Turner, Patrick G Kehoe, Henk-Jan Mutsaerts

Cereb Circ Cogn Behav· January 2025

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Untangling the role of tau in sex hormone responsive cancers: lessons learnt from Alzheimer's disease.
Rachel M Barker, Alfie Chambers, Patrick G Kehoe, Edward Rowe, Claire M Perks

Clin Sci (Lond)· November 2024

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Decentralized clinical trials for medications to reduce the risk of dementia: Consensus report and guidance.
Leanne Howard, Carla Abdelnour, Erin L Abner, Ricardo F Allegri, Hiroko H Dodge, Patrick G Kehoe

Alzheimers Dement· July 2024

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sPDGFRβ and neuroinflammation are associated with AD biomarkers and differ by race: The ASCEND Study.
Brittany Butts, Hanfeng Huang, William T Hu, Patrick Gavin Kehoe, James Scott Miners

Alzheimers Dement· February 2024

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Simulating whole-body vibration for neonatal patients on a tire-coupled road simulator.
Patrick Kehoe, Keely Gibb, Jason Hurley, Robert G Langlois, James R Green

Proc Inst Mech Eng H· February 2024

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Altered Gene Expression Within the Renin-Angiotensin System in Normal Aging and Dementia.
Hannah M Tayler, Robert MacLachlan, Özge Güzel, Robert A Fisher, Olivia A Skrobot, Patrick G Kehoe

J Gerontol A Biol Sci Med Sci· January 2024

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Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study.
Ying Xu, Htein Linn Aung, Randall J Bateman, William S Brooks, Jasmeer Chhatwal, Patrick G Kehoe

Alzheimers Dement· November 2023

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Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by subtypes.
Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Patrick G Kehoe

Proc Natl Acad Sci U S A· September 2023

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The affordability of lecanemab, an amyloid-targeting therapy for Alzheimer's disease: an EADC-EC viewpoint.
Linus Jönsson, Anders Wimo, Ron Handels, Gunilla Johansson, Mercè Boada, Patrick Gavin Kehoe

Lancet Reg Health Eur· June 2023

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Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease.

JAMA Netw Open· May 2023

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Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
Itziar de Rojas, Sonia Moreno-Grau, Niccolo Tesi, Benjamin Grenier-Boley, Victor Andrade, Patrick Gavin Kehoe

Nat Commun· February 2023

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Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer's disease pathology in mouse models of Alzheimer's disease.
Robert MacLachlan, Charles E Evans, Siew Yeen Chai, Mark A Good, Patrick Gavin Kehoe

Aging Brain· December 2022

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Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential.
Xiaojian Shao, Sangeetha Vishweswaraiah, Miroslava Čuperlović-Culf, Ali Yilmaz, Celia M T Greenwood, Patrick G Kehoe

Commun Biol· November 2022

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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.
Yann Le Guen, Michael E Belloy, Benjamin Grenier-Boley, Itziar de Rojas, Atahualpa Castillo-Morales, Patrick G Kehoe

JAMA Neurol· July 2022

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