Publications by authors named "Patrick Loerch"

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Data science in pharmaceutical R&D: the DISRUPT-DS industry roundtable.
Najat S Khan, Thomas Senderovitz, James Weatherall, Janice Branson, Benedikt Egersdoerfer, Patrick Loerch

Nat Rev Drug Discov· September 2024

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Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing.
Luiz Miguel Camargo, Xiaohua Douglas Zhang, Patrick Loerch, Ramon Miguel Caceres, Shane D Marine

PLoS One· November 2015

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Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing.
Luiz Miguel Camargo, Xiaohua Douglas Zhang, Patrick Loerch, Ramon Miguel Caceres, Shane D Marine

PLoS One· September 2015

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Digital transcriptome profiling using selective hexamer priming for cDNA synthesis.
Christopher D Armour, John C Castle, Ronghua Chen, Tomas Babak, Patrick Loerch

Nat Methods· September 2009

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.
Philipp Oberdoerffer, Shaday Michan, Michael McVay, Raul Mostoslavsky, James Vann, Patrick Loerch

Cell· November 2008

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Evolution of the aging brain transcriptome and synaptic regulation.
Patrick M Loerch, Tao Lu, Kelly A Dakin, James M Vann, Adrian Isaacs

PLoS One· October 2008

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The aging brain.
Bruce A Yankner, Tao Lu, Patrick Loerch

Annu Rev Pathol· May 2008

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Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing.
John Castle, Phil Garrett-Engele, Christopher D Armour, Sven J Duenwald, Patrick M Loerch

Genome Biol· August 2004

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Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.
Jason M Johnson, John Castle, Philip Garrett-Engele, Zhengyan Kan, Patrick M Loerch

Science· December 2003

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