Publications by authors named "Patrick Macdonald"

Claim this Profile

Mentions over time

Mentions by platform

Video Views

31,980

Total Likes

433

Extended Reach

144,875

Social Features

26
C
CK2 regulates somatostatin expression in pancreatic delta cells.
Selina Wrublewsky, Annika Clemenz, Anne S Boewe, Cedric Wilden, Caroline Bickelmann, Patrick E MacDonald

Islets· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes.
Theodore Dos Santos, Xiao-Qing Dai, Robert C Jones, Aliya F Spigelman, Hannah M Mummey, Patrick E MacDonald

J Clin Invest· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Supervised machine learning identifies impaired mitochondrial quality control in β cells with development of type 2 diabetes.
Mirza Muhammad Fahd Qadir, Charles Dana, Paul Mauvais-Jarvis, Nazmul Haque, Theodore Dos Santos, Patrick E MacDonald

bioRxiv· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spatially bound functional heterogeneity drives modular organization in β-cell networks.
Maja Duh, Marko Šterk, Lidija Križančić Bombek, Patrick E MacDonald, Andraž Stožer

Biophys J· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heparan sulfate fine-tuned interleukin-1 (IL-1) signaling inhibits insulin secretion of grafted pancreatic islets.
Selina Wrublewsky, Sandra Rother, Franziska Pohlemann, Toni Radanovic, Fabian Junker, Patrick E MacDonald

Sci Adv· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TMEM55A-mediated PI5P signalling regulates alpha cell actin depolymerisation and glucagon secretion.
Xiong Liu, Theodore Dos Santos, Aliya F Spigelman, Shawn Duckett, Nancy Smith, Patrick E MacDonald

Diabetologia· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mechanisms.
Yi-Chun Chen, Nils E Bäck, Jenicia Zhen, Lena Xiong, Mitsuhiro Komba, Patrick E MacDonald

Mol Metab· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular correlates of glycine receptor activity in human β cells.
Amanda Schukarucha Gomes, Cara E Ellis, Aliya F Spigelman, Theodore Dos Santos, Jasmine Maghera, Patrick E MacDonald

Mol Metab· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Gut Microbial Metabolite Butyrate Alleviates IL-1β-Induced Mitochondrial Dysfunction and Oxidative Stress in Pancreatic Islets.
Signe Schultz Pedersen, Richard Denis Maxime De Mets, Joana Mendes Lopes de Melo, Andrea Irazoki, Patrick E MacDonald

FASEB J· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors.
Nidheesh Dadheech, Mario Bermúdez de León, Zofia Czarnecka, Nerea Cuesta-Gomez, Ila Tewari Jasra, Patrick MacDonald

NPJ Regen Med· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cisplatin Exposure Dysregulates Insulin Secretion in Male and Female Mice.
Lahari Basu, Lili Grieco-St-Pierre, Ma Enrica Angela Ching, John D H Stead, Antonio A Hanson, Patrick E MacDonald

Diabetes· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lessons from a model: early glucagon dysfunction in type 2 diabetes.
Shawn Duckett, Patrick E MacDonald

Pflugers Arch· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HumanIslets.com: Improving accessibility, integration, and usability of human research islet data.
Jessica D Ewald, Yao Lu, Cara E Ellis, Jessica Worton, Jelena Kolic, Patrick E MacDonald

Cell Metab· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Scalable Bioreactor-based Suspension Approach to Generate Stem Cell-derived Islets From Healthy Donor-derived iPSCs.
Kevin Verhoeff, Nerea Cuesta-Gomez, Jasmine Maghera, Nidheesh Dadheech, Rena Pawlick, Patrick E MacDonald

Transplantation· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Q
Quantifying glucose uptake at the single cell level with confocal microscopy reveals significant variability within and across individuals.
Joel D Paprocki, Patrick J Macdonald, Yongjin Xu, Alan Cheng, Timothy C Dunn

Sci Rep· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human research islet cell culture outcomes at the Alberta Diabetes Institute IsletCore.
James G Lyon, Alice Lj Carr, Nancy P Smith, Braulio Marfil-Garza, Aliya F Spigelman, Patrick E MacDonald

Islets· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TMEM55A-mediated PI5P signaling regulates α-cell actin depolymerization and glucagon secretion.
Xiong Liu, Theodore Dos Santos, Aliya F Spigelman, Shawn Duckett, Nancy Smith, Patrick E MacDonald

bioRxiv· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells.
Carmen L Bayly, Xiao-Qing Dai, Cuilan Nian, Paul C Orban, C Bruce Verchere, Patrick E MacDonald

Mol Metab· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice.
Cristiane Dos Santos, Amanda Cambraia, Shristi Shrestha, Melanie Cutler, Matthew Cottam, Patrick E MacDonald

Nat Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk.
Hannah M Mummey, Weston Elison, Katha Korgaonkar, Ruth M Elgamal, Parul Kudtarkar, Patrick E MacDonald

bioRxiv· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation.
Zhiqiang Pang, Yao Lu, Guangyan Zhou, Fiona Hui, Lei Xu, Patrick E MacDonald

Nucleic Acids Res· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluating Islet Cell Isolation and Transplantation From Donors Following Medical Assistance in Dying.
Alessandro Parente, Kevin Verhoeff, Tatsuya Kin, Joshua Hefler, Braulio A Marfil-Garza, Patrick E MacDonald

Transplant Direct· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HumanIslets: An integrated platform for human islet data access and analysis.
Jessica D Ewald, Yao Lu, Cara E Ellis, Jessica Worton, Jelena Kolic, Patrick E MacDonald

bioRxiv· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
Sara M Willems, Natasha H J Ng, Juan Fernandez, Rebecca S Fine, Eleanor Wheeler, Patrick E MacDonald

Wellcome Open Res· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis