Publications by authors named "Patrick Roussel"

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The natural diyne-furan fatty acid EV-086 is an inhibitor of fungal delta-9 fatty acid desaturation with efficacy in a model of skin dermatophytosis.
Philipp Knechtle, Melanie Diefenbacher, Katrine B V Greve, Federico Brianza, Christophe Folly, Patrick Roussel

Antimicrob Agents Chemother· September 2014

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Identification of potent pyrazolo[4,3-h]quinazoline-3-carboxamides as multi-cyclin-dependent kinase inhibitors.
Gabriella Traquandi, Marina Ciomei, Dario Ballinari, Elena Casale, Nicoletta Colombo, Patrick Roussel

J Med Chem· March 2010

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Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing.
Maria Gabriella Brasca, Clara Albanese, Rachele Alzani, Raffaella Amici, Nilla Avanzi, Patrick Roussel

Bioorg Med Chem· March 2010

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Crystallographic analysis of bacterial signal peptidase in ternary complex with arylomycin A2 and a beta-sultam inhibitor.
Chuanyun Luo, Patrick Roussel, Jürg Dreier, Malcolm G P Page, Mark Paetzel

Biochemistry· September 2009

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Investigation of the species-dependent in vitro metabolism of BAL30630 by stable isotope labeling and isotope exchange experiments analyzed by capillary liquid chromatography coupled to mass spectrometry.
Mathias Wind, Helge Grunwald, Klaus Gebhardt, Klaus Illig, Jochen Spickermann, Patrick Roussel

J Chromatogr A· May 2009

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6-Substituted pyrrolo[3,4-c]pyrazoles: an improved class of CDK2 inhibitors.
Maria Gabriella Brasca, Clara Albanese, Raffaella Amici, Dario Ballinari, Luca Corti, Patrick Roussel

ChemMedChem· June 2007

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Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators.
Markus Thor, Katarina Beierlein, Graeme Dykes, Anna Lena Gustavsson, Jessica Heidrich, Patrick Roussel

Bioorg Med Chem Lett· December 2002

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Synthesis and antiaggregant properties of Stabilized analogues of polyunsaturated fatty acid metabolites.
Ali Hachem, Patrick Roussel, Eric Ménager, Danielle Grée, Yves Le Floc'h

Bioorg Med Chem Lett· September 2002

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