Publications by authors named "Patrick Steel"

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Microplate-Based Enzymatic Activity Assay Protocol Powered by Activity-Based Probes.
Exequiel O J Porta, Karunakaran Kalesh, Jaime A Isern, Patrick G Steel

Methods Mol Biol· June 2025

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Profiling Serine Hydrolases in the Leishmania Host-Pathogen Interactome Using Cell-Permeable Activity-Based Fluorophosphonate Probes.
Jaime A Isern, Exequiel O J Porta, Karunakaran Kalesh, Zisis Koutsogiannis, Davide Cazzola, Patrick G Steel

Chembiochem· May 2025

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Simple accessible clemastine fumarate analogues as effective antileishmanials.
Rebecca L Charlton, Douglas O Escrivani, Christopher Brown, Niranjan Thota, Victor S Agostino, Patrick G Steel

RSC Med Chem· April 2025

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Nanocrystallization Effectively Improves the Oral Efficacy of an Antileishmanial Chalcone.
Maria Paula Gonçalves Borsodi, Wallace Pacienza-Lima, Jaqueline Correia Villaça Menezes, Douglas Escrivani-Oliveira, Natalia Arruda-Costa, Patrick G Steel

Pharmaceutics· March 2025

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Applications of Transition Metal-Catalyzed -Fluorine-Directed C-H Functionalization of (Poly)fluoroarenes in Organic Synthesis.
Yudha P Budiman, Robin N Perutz, Patrick G Steel, Udo Radius, Todd B Marder

Chem Rev· April 2024

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Assessing Dose-Exposure-Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach.
Shadrack J Madu, Ke Wang, Siri Kalyan Chirumamilla, David B Turner, Patrick G Steel

Pharm Res· December 2023

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Inhibition of HSP90 distinctively modulates the global phosphoproteome of developmental stages.
Exequiel O Porta, Liqian Gao, Paul W Denny, Patrick G Steel, Karunakaran Kalesh

Microbiol Spectr· December 2023

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Synthesis and vectorial functionalisation of pyrazolo[3,4-]pyridines.
Elizabeth V Bedwell, Flavio da Silva Emery, Giuliano C Clososki, Patrick G Steel

RSC Adv· November 2023

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Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity.
Nailma S A Dos Santos, Carlos F Estevez-Castro, Juan P Macedo, Daniela F Chame, Thiago Castro-Gomes, Patrick G Steel

PLoS Negl Trop Dis· September 2023

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Activity-based protein profiling: A graphical review.
Exequiel O J Porta, Patrick G Steel

Curr Res Pharmacol Drug Discov· August 2023

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Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities.
Exequiel O J Porta, Karunakaran Kalesh, Patrick G Steel

Front Pharmacol· July 2023

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Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine.
Amy V Hall, Isobel E F Gostick, Dmitry S Yufit, Gloria Y Marchant, Preyanthiny Kirubakaran, Patrick G Steel

Cryst Growth Des· October 2022

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Discovery of Druggable Serine Proteases by Activity-Based Protein Profiling.
Exequiel O J Porta, Jaime A Isern, Karunakaran Kalesh, Patrick G Steel

Front Pharmacol· July 2022

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Plant growth promotion by the interaction of a novel synthetic small molecule with GA-DELLA function.
Nur Afiqah Sukiran, Susanna Pollastri, Patrick G Steel, Marc R Knight

Plant Direct· April 2022

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First-Row d-Block Element-Catalyzed Carbon-Boron Bond Formation and Related Processes.
Shubhankar Kumar Bose, Lujia Mao, Laura Kuehn, Udo Radius, Jan Nekvinda, Patrick G Steel

Chem Rev· November 2021

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Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance.
Maria Schwarz, Rebecca F M Eno, Stefanie Freitag-Pohl, Christopher R Coxon, Hannah E Straker, Patrick G Steel

Org Biomol Chem· November 2021

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Chalcones identify cTXNPx as a potential antileishmanial drug target.
Douglas O Escrivani, Rebecca L Charlton, Marjolly B Caruso, Gabriela A Burle-Caldas, Maria Paula G Borsodi, Patrick G Steel

PLoS Negl Trop Dis· November 2021

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Iridium-Catalysed C-H Borylation of Heteroarenes: Balancing Steric and Electronic Regiocontrol.
Jay S Wright, Peter J H Scott, Patrick G Steel

Angew Chem Int Ed Engl· February 2021

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Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Inositol Phosphorylceramide Synthase.
John G M Mina, Rebecca L Charlton, Edubiel Alpizar-Sosa, Douglas O Escrivani, Christopher Brown, Patrick G Steel

ACS Infect Dis· January 2021

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Single-dose treatment for cutaneous leishmaniasis with an easily synthesized chalcone entrapped in polymeric microparticles.
Ariane J Sousa-Batista, Natalia Arruda-Costa, Douglas O Escrivani, Franceline Reynaud, Patrick G Steel

Parasitology· August 2020

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Basal stomatal aperture is regulated by GA-DELLAs in Arabidopsis.
Nur Afiqah Sukiran, Patrick G Steel, Marc R Knight

J Plant Physiol· July 2020

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Encapsulation in lipid-core nanocapsules improves topical treatment with the potent antileishmanial compound CH8.
Douglas O Escrivani, Milene Valéria Lopes, Fernanda Poletto, Stela Regina Ferrarini, Ariane J Sousa-Batista, Patrick G Steel

Nanomedicine· February 2020

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Expression levels of inositol phosphorylceramide synthase modulate plant responses to biotic and abiotic stress in Arabidopsis thaliana.
Elizabeth C Pinneh, Rhea Stoppel, Heather Knight, Marc R Knight, Patrick G Steel

PLoS One· January 2020

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Impact of heat and drought stress on peroxisome proliferation in quinoa.
Leonardo Hinojosa, Marwa N M E Sanad, David E Jarvis, Patrick Steel, Kevin Murphy

Plant J· September 2019

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The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity.
Elizabeth C Pinneh, John G Mina, Michael J R Stark, Stephen D Lindell, Peter Luemmen, Patrick G Steel

Sci Rep· May 2019

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