Publications by authors named "Patrick Stoy"

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Real-World Safety and Health Care Resource Utilization of Teclistamab Under an Outpatient Model for Step-Up Dosing Administration.
Tyler B Sandahl, Scott A Soefje, Rafael Fonseca, Sikander Ailawadhi, Ricardo Parrondo, Patrick Stoy

JCO Oncol Pract· May 2025

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Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf.
Jaclyn R Patterson, Alan P Graves, Patrick Stoy, Mui Cheung, Tina A Desai

J Med Chem· November 2021

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Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo.
Xiaoping Xu, Navin Goyal, Melissa H Costell, Theresa Roethke, Christian H James, Patrick Stoy

J Pharmacol Exp Ther· March 2021

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Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry.
Andrew Jordan, Patrick Stoy, Helen F Sneddon

Chem Rev· February 2021

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Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions.
Jaclyn R Patterson, Lamont R Terrell, Carla A Donatelli, Dennis A Holt, Larry J Jolivette, Patrick Stoy

J Med Chem· December 2020

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Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4).
Carl A Brooks, Linda S Barton, David J Behm, Hilary S Eidam, Ryan M Fox, Patrick Stoy

ACS Med Chem Lett· August 2019

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Advances in Lead Generation.
Joerg Holenz, Patrick Stoy

Bioorg Med Chem Lett· February 2019

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Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4).
Edward J Brnardic, Guosen Ye, Carl Brooks, Carla Donatelli, Linda Barton, Patrick Stoy

J Med Chem· November 2018

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Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.
Ronald J Vagnozzi, Gregory J Gatto, Lara S Kallander, Nicholas E Hoffman, Karthik Mallilankaraman, Patrick Stoy

Sci Transl Med· October 2013

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Improving the developability profile of pyrrolidine progesterone receptor partial agonists.
Lara S Kallander, David G Washburn, Tram H Hoang, James S Frazee, Patrick Stoy

Bioorg Med Chem Lett· January 2010

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Fluorous affinity purification of oligonucleotides.
William H Pearson, David A Berry, Patrick Stoy, Kee-Yong Jung, Anthony D Sercel

J Org Chem· September 2005

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Total synthesis of the Kopsia lapidilecta alkaloid (+/-)-lapidilectine B.
William H Pearson, Ill Young Lee, Yuan Mi, Patrick Stoy

J Org Chem· December 2004

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Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction.
Yingzhi Bi, Patrick Stoy, Leonard Adam, Bin He, John Krupinski

Bioorg Med Chem Lett· March 2004

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Azomethine ylides from tin-substituted cyclic carbinol amides: a new route to highly substituted pyrrolizidines.
William H Pearson, Amber Dietz, Patrick Stoy

Org Lett· March 2004

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A three-component, one-pot synthesis of indolizidines and related heterocycles via the [3+2] cycloaddition of nonstabilized azomethine ylides.
William H Pearson, Patrick Stoy, Yuan Mi

J Org Chem· March 2004

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