Publications by authors named "Patrick Tan"

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Determinants of diagnostic yield in a multi-ethnic Asian inherited retinal disease cohort.
Jane Andrea Lieviant, Choi Mun Chan, Yasmin Bylstra, Kanika Jain, Jing Xian Teo, Tang Wei Chao, Tien-En Tan, Patrick Tan

Eur J Hum Genet· December 2025

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Spatial profiling of patient-matched HER2 positive gastric cancer reveals resistance mechanisms to targeted therapy.
Taotao Sheng, Raghav Sundar, Supriya Srivastava, Xuewen Ong, Su Ting Tay, Angie Lay Keng Tan, Patrick Tan

Gut· October 2025

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Predictive capabilities of polygenic scores in an East-Asian population-based cohort: the Singapore Chinese health study.
Xuling Chang, Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Patrick Tan

Commun Biol· August 2025

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Correction: Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer.
Ryan Yong Kiat Tay, Manavi Sachdeva, Haoran Ma, Young-Woo Kim, Myeong-Cherl Kook, Patrick Tan

Gastric Cancer· July 2025

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Spatial Heterogeneity, Stromal Phenotypes, and Therapeutic Vulnerabilities in Colorectal Cancer Peritoneal Metastasis.
Chin-Ann Johnny Ong, Joseph J Zhao, Ying Liu, Supriya Srivastava, Daryl K A Chia, Qiu Xuan Tan, Joey W S Tan, Angie Tan, Patrick Tan

Clin Cancer Res· June 2025

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Glioportal: a comprehensive transcriptomic resource unveiling ligand-mediated mesenchymal transition in glioblastoma.
Qing You Pang, Wisna Novera, Lynnette Wei Hsien Koh, Yuk Kien Chong, See Wee Lim, Nguan Soon Tan, Patrick Tan, Carol Tang

Neuro Oncol· June 2025

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Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer.
Ryan Yong Kiat Tay, Manavi Sachdeva, Haoran Ma, Young-Woo Kim, Myeong-Cherl Kook, Patrick Tan

Gastric Cancer· May 2025

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Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.
Nilanjana Sadhu, Rinkoo Dalan, Pritesh R Jain, Chang Jie Mick Lee, Leroy Sivappiragasam Pakkiri, Patrick Tan

Nat Cardiovasc Res· May 2025

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Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution.
Haoran Ma, Supriya Srivastava, Shamaine Wei Ting Ho, Chang Xu, Benedict Shi Xiang Lian, Angie Lay Keng Tan, Patrick Tan

Cancer Discov· April 2025

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Genomic garden: From societal and scientific impacts to biodiversity conservation.
Abner Herbert Lim, Cedric Chuan Young Ng, Jing Han Hong, Ewe Choon Lee, Kenneth Kwek, Patrick Tan

Cell Genom· April 2025

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The expanding global genomics landscape: Converging priorities from national genomics programs.
Caitlin Howley, Matilda A Haas, Wadha A Al Muftah, Robert B Annan, Eric D Green, Patrick Tan

Am J Hum Genet· April 2025

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A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.
Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty, Denis Odinokov, Probhonjon Baruah, Tira J Tan, Patrick Tan, Daniel Tan, Iain Beehuat Tan

Nat Biomed Eng· March 2025

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EZH2 functional dichotomy in reactive oxygen species-stratified glioblastoma.
Lynnette Wei Hsien Koh, Qing You Pang, Wisna Novera, See Wee Lim, Yuk Kien Chong, Patrick Tan, Nguan Soon Tan, Carol Tang

Neuro Oncol· February 2025

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IQGAP3 signalling mediates intratumoral functional heterogeneity to enhance malignant growth.
Mitsuhiro Shimura, Junichi Matsuo, ShuChin Pang, Nawaphat Jangphattananont, Aashiq Hussain, Patrick Tan

Gut· February 2025

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Predictive Capabilities of Polygenic Scores in an East-Asian Population-based Cohort: The Singapore Chinese Health Study.
Xuling Chang, Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Patrick Tan

medRxiv· February 2025

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Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations.
Pritesh R Jain, Hong Kiat Ng, Darwin Tay, Theresia Mina, Dorrain Low, Patrick Tan

medRxiv· February 2025

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Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling.
Xi Xiao Huang, Ley Moy Ng, Po-Hsien Lee, Peiyong Guan, Mun Juinn Chow, Kenric Yi Shu Tan, Patrick Tan, Puay Hoon Tan

NPJ Breast Cancer· January 2025

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Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases.
Joseph J Zhao, Chin-Ann Johnny Ong, Supriya Srivastava, Daryl Kai Ann Chia, Haoran Ma, Angie Lay Keng Tan, Qiu Xuan Tan, Joey Wee-Shan Tan, Patrick Tan

Gastroenterology· December 2024

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The Causal Effect of Adult Height on Late-Life Handgrip Strength: The Singapore Chinese Health Study.
Xuling Chang, Kevin Yiqiang Chua, Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Patrick Tan

J Gerontol A Biol Sci Med Sci· November 2024

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A Catalogue of Structural Variation across Ancestrally Diverse Asian Genomes.
Joanna Hui Juan Tan, Zhihui Li, Mar Gonzalez Porta, Ramesh Rajaby, Weng Khong Lim, Ye An Tan, Patrick Tan

Nat Commun· November 2024

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Unveiling the prognostic significance of malignant ascites in advanced gastrointestinal cancers: a marker of peritoneal carcinomatosis burden.
Leonardo Provenzano, Yong Xiang Gwee, Veronica Conca, Sara Lonardi, Silvia Bozzarelli, Patrick Tan

Ther Adv Med Oncol· November 2024

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Integrated enhancer regulatory network by enhancer-promoter looping in gastric cancer.
Tianhui Zhu, Atsushi Okabe, Genki Usui, Ryoji Fujiki, Daichi Komiyama, Patrick Tan

NAR Cancer· June 2024

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Machine learning identifies activation of RUNX/AP-1 as drivers of mesenchymal and fibrotic regulatory programs in gastric cancer.
Milad Razavi-Mohseni, Weitai Huang, Yu A Guo, Dustin Shigaki, Shamaine Wei Ting Ho, Patrick Tan

Genome Res· June 2024

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Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel ROS1 fusion gene and PBX1 as prognostic marker.
Patrick S Plum, Timo Hess, Denis Bertrand, Isabelle Morgenstern, Oscar Velazquez Camacho, Patrick Tan

Clin Transl Med· June 2024

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Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma.
Harue Mizokami, Atsushi Okabe, Ruchi Choudhary, Masato Mima, Kenta Saeda, Patrick Tan

EBioMedicine· April 2024

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