Publications by authors named "Paul Blakemore"

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Total Synthesis of Chalaniline A: An Aminofulvene Fused Chromone from Vorinostat-Treated Fungus sp. 6661.
Pannaporn Prapapongpan, Veerapattha Vanthiya, Oh-Seok Kwon, Lev N Zakharov, Sandra Loesgen, Paul R Blakemore

J Org Chem· October 2024

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Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice.
Ines L Paraiso, Luce M Mattio, Armando Alcázar Magaña, Jaewoo Choi, Layhna S Plagmann, Paul R Blakemore

ACS Pharmacol Transl Sci· December 2021

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Retrospective validation of a risk stratification tool developed for the management of patients with blunt chest trauma (the STUMBL score).
Saptarshi Mukerji, Eunicia Tan, Charlotte May, Christina Micanovic, Paul Blakemore

Emerg Med Australas· October 2021

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An important reminder regarding ketamine's safety profile.
Paul Blakemore

Emerg Med Australas· October 2021

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Total Synthesis of Chalaniline B: An Antibiotic Aminoxanthone from Vorinostat-Treated Fungus sp. 6661.
Mahsa Khoshbakht, Bongkotrat Thanaussavadate, Chenxi Zhu, Yang Cao, Lev N Zakharov, Paul R Blakemore

J Org Chem· June 2021

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Synthesis of a P-Glycoprotein Inhibitor and Its High-Energy ()-Isomer by Carbenoid Eliminative Cross-Coupling.
Subhash D Tanpure, Mohamed F El-Mansy, Paul R Blakemore

Org Lett· April 2020

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Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.
Yang Zhang, Gerd Bobe, Johana S Revel, Richard R Rodrigues, Thomas J Sharpton, Paul R Blakemore

Mol Nutr Food Res· January 2020

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Biological evaluation of molecules of the azaBINOL class as antiviral agents: Inhibition of HIV-1 RNase H activity by 7-isopropoxy-8-(naphth-1-yl)quinoline.
Ross D Overacker, Somdev Banerjee, George F Neuhaus, Selena Milicevic Sephton, Alexander Herrmann, Paul R Blakemore

Bioorg Med Chem· August 2019

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Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.
Ines L Paraiso, Layhna S Plagmann, Liping Yang, Ryszard Zielke, Adrian F Gombart, Paul R Blakemore

Mol Nutr Food Res· January 2019

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Formation of Olefins by Eliminative Dimerization and Eliminative Cross-Coupling of Carbenoids: A Stereochemical Exercise.
Paul R Blakemore, Reinhard W Hoffmann

Angew Chem Int Ed Engl· January 2018

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Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice.
Cristobal L Miranda, Lance A Johnson, Oriane de Montgolfier, Valerie D Elias, Lea S Ullrich, Paul R Blakemore

Sci Rep· January 2018

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Total synthesis of [ C] -, [ C] -, and [ C] -isotopomers of xanthohumol, the principal prenylflavonoid from hops.
Duncan C Ellinwood, Mohamed F El-Mansy, Layhna S Plagmann, Jan F Stevens, Claudia S Maier, Paul R Blakemore

J Labelled Comp Radiopharm· December 2017

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Stereospecific Synthesis of Alkenes by Eliminative Cross-Coupling of Enantioenriched sp(3) -Hybridized Carbenoids.
Zhenhua Wu, Xun Sun, Kristin Potter, Yang Cao, Lev N Zakharov, Paul R Blakemore

Angew Chem Int Ed Engl· September 2016

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Trace Analysis of Surfactants in Corexit Oil Dispersant Formulations and Seawater.
Benjamin J Place, Matt J Perkins, Ewan Sinclair, Adam L Barsamian, Paul R Blakemore

Deep Sea Res 2 Top Stud Oceanogr· July 2016

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Enantioselective synthesis of α-phenyl- and α-(dimethylphenylsilyl)alkylboronic esters by ligand mediated stereoinductive reagent-controlled homologation using configurationally labile carbenoids.
Adam L Barsamian, Zhenhua Wu, Paul R Blakemore

Org Biomol Chem· March 2015

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Regioselective syntheses of [13C]4-labelled sodium 1-carboxy-2-(2-ethylhexyloxycarbonyl)ethanesulfonate and sodium 2-carboxy-1-(2-ethylhexyloxycarbonyl)ethanesulfonate from [13C]4-maleic anhydride.
Adam L Barsamian, Matt J Perkins, Jennifer A Field, Paul R Blakemore

J Labelled Comp Radiopharm· May 2014

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Investigation of functionalized α-chloroalkyllithiums for a stereospecific reagent-controlled homologation approach to the analgesic alkaloid (-)-epibatidine.
Christopher R Emerson, Lev N Zakharov, Paul R Blakemore

Chemistry· November 2013

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Programmed synthesis of a contiguous stereotriad motif by triple stereospecific reagent-controlled homologation.
Xun Sun, Paul R Blakemore

Org Lett· September 2013

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Synthesis of 7,7'-dihydroxy-8,8'-biquinolyl (azaBINOL) via Pd-catalyzed directed double C-H functionalization of 8,8'-biquinolyl: emergence of an atropos from a tropos state.
Chao Wang, Darrin M Flanigan, Lev N Zakharov, Paul R Blakemore

Org Lett· August 2011

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Iterative stereospecific reagent-controlled homologation using a functionalized α-chloroalkyllithium: synthesis of cyclic targets related to epibatidine.
Christopher R Emerson, Lev N Zakharov, Paul R Blakemore

Org Lett· March 2011

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Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative.
Mark A Sephton, Christopher R Emerson, Lev N Zakharov, Paul R Blakemore

Chem Commun (Camb)· March 2010

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Total synthesis of (+/-)-alpha-isosparteine, (+/-)-beta-isosparteine, and (+/-)-sparteine from a common tetraoxobispidine intermediate.
Neil R Norcross, John P Melbardis, Margarita Ferris Solera, Mark A Sephton, Colin Kilner, Paul R Blakemore

J Org Chem· October 2008

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Enzymatic resolution of 7,7'-dihydroxy-8,8'- biquinolyl dipentanoate and its conversion to 2,2'-di-tert-butyl-7,7'-dihydroxy-8,8'-biquinolyl.
Paul R Blakemore, Selena D Milicevic, Lev N Zakharov

J Org Chem· November 2007

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Iterative stereospecific reagent-controlled homologation of pinacol boronates by enantioenriched alpha-chloroalkyllithium reagents.
Paul R Blakemore, Matthew S Burge

J Am Chem Soc· March 2007

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Resolution, enantiomerization kinetics, and chiroptical properties of 7,7'-dihydroxy-8,8'-biquinolyl.
Paul R Blakemore, Colin Kilner, Selena D Milicevic

J Org Chem· October 2006

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