Publications by authors named "Paul Blower"

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Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
Anh-Nhan Pham, Paul E Blower, Omar Alvarado, Ranadheer Ravula, Peter W Gout

J Pharmacol Exp Ther· March 2010

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Pharmacogenomics approach reveals MRP1 (ABCC1)-mediated resistance to geldanamycins.
Anh-Nhan Pham, Jeffrey Wang, Jialong Fang, Xin Gao, Yilong Zhang, Paul E Blower

Pharm Res· April 2009

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In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Ogechi N Ikediobi, Mark Reimers, Steffen Durinck, Paul E Blower, Andrew P Futreal

Mol Cancer Ther· June 2008

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MicroRNAs modulate the chemosensitivity of tumor cells.
Paul E Blower, Ji-Hyun Chung, Joseph S Verducci, Shili Lin, Jong-Kook Park

Mol Cancer Ther· January 2008

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Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.
Ruqing Liu, Paul E Blower, Anh-Nhan Pham, Jialong Fang, Zunyan Dai

Mol Pharmacol· December 2007

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Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1.
Ying Huang, Paul E Blower, Ruqing Liu, Zunyan Dai, Anh-Nhan Pham

Pharm Res· September 2007

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MicroRNA expression profiles for the NCI-60 cancer cell panel.
Paul E Blower, Joseph S Verducci, Shili Lin, Jin Zhou, Ji-Hyun Chung

Mol Cancer Ther· May 2007

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Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-.
Zunyan Dai, Ying Huang, Wolfgang Sadee, Paul Blower

J Med Chem· April 2007

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Decision tree methods in pharmaceutical research.
Paul E Blower, Kevin P Cross

Curr Top Med Chem· March 2006

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Comparison of methods for sequential screening of large compound sets.
Paul E Blower, Kevin P Cross, Gabriel S Eichler, Glenn J Myatt, John N Weinstein

Comb Chem High Throughput Screen· February 2006

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Building predictive models for protein tyrosine phosphatase 1B inhibitors based on discriminating structural features by reassembling medicinal chemistry building blocks.
Chihae Yang, Kevin Cross, Glenn J Myatt, Paul E Blower, James F Rathman

J Med Chem· November 2004

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Systematic analysis of large screening sets in drug discovery.
Paul E Blower, Kevin P Cross, Michael A Fligner, Glenn J Myatt, Joseph S Verducci

Curr Drug Discov Technol· January 2004

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Finding discriminating structural features by reassembling common building blocks.
Kevin P Cross, Glenn Myatt, Chihae Yang, Michael A Fligner, Joseph S Verducci, Paul E Blower

J Med Chem· October 2003

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On combining recursive partitioning and simulated annealing to detect groups of biologically active compounds.
Paul Blower, Michael Fligner, Joseph Verducci, Jeffrey Bjoraker

J Chem Inf Comput Sci· May 2002

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Multiscale and Bayesian approaches to data analysis in genomics high-throughput screening.
Chihae Yang, Bhavik R Bakshi, James F Rathman, Paul E Blower

Curr Opin Drug Discov Devel· May 2002

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