Publications by authors named "Paul D Coleman"

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Frontal cortex pyramidal neuron expression profiles differentiate the prodromal stage from progressive degeneration across the Alzheimer's disease spectrum.
Amanda Labuza, Melissa J Alldred, Harshitha Pidikiti, Michael H Malek-Ahmadi, Sang Han Lee, Paul D Coleman

Alzheimers Dement· July 2025

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Massive changes in gene expression and their cause(s) can be a unifying principle in the pathobiology of Alzheimer's disease.
Paul D Coleman, Elaine Delvaux, Jeffrey H Kordower, Ashley Boehringer, Carol J Huseby

Alzheimers Dement· February 2025

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Alzheimer's disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway.
Kyonghwan Choe, Muhammad Ali, Roy Lardenoije, Renzo J M Riemens, Ehsan Pishva, Paul D Coleman

Alzheimers Res Ther· November 2024

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Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer's Disease.
Ignazio S Piras, Danielle Brokaw, Yinfei Kong, Daniel J Weisenberger, Jonida Krate, Paul D Coleman

Cell Mol Neurobiol· July 2023

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Blood RNA transcripts reveal similar and differential alterations in fundamental cellular processes in Alzheimer's disease and other neurodegenerative diseases.
Carol J Huseby, Elaine Delvaux, Danielle L Brokaw, Paul D Coleman

Alzheimers Dement· June 2023

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Intracellular Amyloid-β Detection from Human Brain Sections Using a Microfluidic Immunoassay in Tandem with MALDI-MS.
Jorvani Cruz Villarreal, Keegan Kow, Brian Pham, Ana Egatz-Gomez, Todd R Sandrin, Paul D Coleman

Anal Chem· April 2023

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Blood Transcript Biomarkers Selected by Machine Learning Algorithm Classify Neurodegenerative Diseases including Alzheimer's Disease.
Carol J Huseby, Elaine Delvaux, Danielle L Brokaw, Paul D Coleman

Biomolecules· October 2022

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MIMAS: microfluidic platform in tandem with MALDI mass spectrometry for protein quantification from small cell ensembles.
Jorvani Cruz Villarreal, Rory Kruithoff, Ana Egatz-Gomez, Paul D Coleman, Robert Ros

Anal Bioanal Chem· May 2022

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A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
Rebecca G Smith, Ehsan Pishva, Gemma Shireby, Adam R Smith, Janou A Y Roubroeks, Paul D Coleman

Nat Commun· June 2021

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Highly Sensitive and Multiplexed Protein Imaging With Cleavable Fluorescent Tyramide Reveals Human Neuronal Heterogeneity.
Renjie Liao, Manas Mondal, Christopher D Nazaroff, Diego Mastroeni, Paul D Coleman

Front Cell Dev Biol· January 2021

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Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets.
Danielle L Brokaw, Ignazio S Piras, Diego Mastroeni, Daniel J Weisenberger, Jennifer Nolz, Paul D Coleman

Neurobiol Aging· November 2020

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Transcriptome Changes in the Alzheimer's Disease Middle Temporal Gyrus: Importance of RNA Metabolism and Mitochondria-Associated Membrane Genes.
Ignazio S Piras, Jonida Krate, Elaine Delvaux, Jennifer Nolz, Diego F Mastroeni, Paul D Coleman

J Alzheimers Dis· October 2020

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Highly Sensitive and Multiplexed In-Situ Protein Profiling with Cleavable Fluorescent Streptavidin.
Renjie Liao, Thai Pham, Diego Mastroeni, Paul D Coleman, Joshua Labaer

Cells· April 2020

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AmpliSeq Transcriptome of Laser Captured Neurons from Alzheimer Brain: Comparison of Single Cell Versus Neuron Pools.
Wenjun Deng, Changhong Xing, Rob David, Diego Mastroeni, MingMing Ning, Paul D Coleman

Aging Dis· December 2019

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Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.
Roy Lardenoije, Janou A Y Roubroeks, Ehsan Pishva, Markus Leber, Holger Wagner, Paul D Coleman

Clin Epigenetics· November 2019

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Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus.
Ignazio S Piras, Jonida Krate, Elaine Delvaux, Jennifer Nolz, Matthew D De Both, Paul D Coleman

Brain Res· September 2019

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Gradual hypertension induction in middle-aged Cyp1a1-Ren2 transgenic rats produces significant impairments in spatial learning.
Mari N Willeman, Monica K Chawla, Marc A Zempare, Lauren A Biwer, Lan T Hoang, Paul D Coleman

Physiol Rep· March 2019

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Upregulation of histone deacetylase 2 in laser capture nigral microglia in Parkinson's disease.
Yuyan Tan, Elaine Delvaux, Jennifer Nolz, Paul D Coleman, Shengdi Chen

Neurobiol Aging· August 2018

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Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs.
Diego Mastroeni, Jennifer Nolz, Omar M Khdour, Shobana Sekar, Elaine Delvaux, Paul D Coleman

Alzheimers Dement· June 2018

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Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain.
Diego Mastroeni, Jennifer Nolz, Shobana Sekar, Elaine Delvaux, Geidy Serrano, Paul D Coleman

Neurobiol Aging· March 2018

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Correction: ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Paul D Coleman

PLoS One· January 2018

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Multivariate analyses of peripheral blood leukocyte transcripts distinguish Alzheimer's, Parkinson's, control, and those at risk for developing Alzheimer's.
Elaine Delvaux, Diego Mastroeni, Jennifer Nolz, Nienwen Chow, Marwan Sabbagh, Paul D Coleman

Neurobiol Aging· October 2017

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A call for new approaches to Alzheimer's disease research.
Paul D Coleman, Diego Mastroeni

Neurobiol Aging· September 2017

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ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Paul D Coleman

PLoS One· September 2017

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Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease.
Diego Mastroeni, Omar M Khdour, Elaine Delvaux, Jennifer Nolz, Gary Olsen, Paul D Coleman

Alzheimers Dement· May 2017

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