Publications by authors named "Paul D Donohoue"

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High-Specificity CRISPR-Mediated Genome Engineering in Anti-BCMA Allogeneic CAR T Cells Suppresses Allograft Rejection in Preclinical Models.
Émilie Degagné, Paul D Donohoue, Suparna Roy, Jessica Scherer, Tristan W Fowler

Cancer Immunol Res· April 2024

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Author Correction: Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Peter Cameron, Chris K Fuller, Paul D Donohoue, Brittnee N Jones, Matthew S Thompson

Nat Methods· December 2023

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Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness.
Elaine Lau, George Kwong, Tristan W Fowler, Bee-Chun Sun, Paul D Donohoue

Cytotherapy· July 2023

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Structural basis for Cas9 off-target activity.
Martin Pacesa, Chun-Han Lin, Antoine Cléry, Aakash Saha, Pablo R Arantes, Paul D Donohoue

Cell· October 2022

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Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Paul D Donohoue, Martin Pacesa, Elaine Lau, Bastien Vidal, Matthew J Irby

Mol Cell· September 2021

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Harnessing type I CRISPR-Cas systems for genome engineering in human cells.
Peter Cameron, Mary M Coons, Sanne E Klompe, Alexandra M Lied, Stephen C Smith, Paul D Donohoue

Nat Biotechnol· December 2019

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NmeCas9 is an intrinsically high-fidelity genome-editing platform.
Nadia Amrani, Xin D Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Paul D Donohoue

Genome Biol· December 2018

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Advances in Industrial Biotechnology Using CRISPR-Cas Systems.
Paul D Donohoue, Rodolphe Barrangou, Andrew P May

Trends Biotechnol· February 2018

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Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Peter Cameron, Chris K Fuller, Paul D Donohoue, Brittnee N Jones, Matthew S Thompson

Nat Methods· June 2017

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Guide RNA functional modules direct Cas9 activity and orthogonality.
Alexandra E Briner, Paul D Donohoue, Ahmed A Gomaa, Kurt Selle, Euan M Slorach

Mol Cell· October 2014

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Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform.
Maria Enquist-Newman, Ann Marie E Faust, Daniel D Bravo, Christine Nicole S Santos, Ryan M Raisner, Paul D Donohoue

Nature· January 2014

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Kinetic properties of ATP sulfurylase and APS kinase from Thiobacillus denitrificans.
Sean C Gay, Jennifer L Fribourgh, Paul D Donohoue, Irwin H Segel, Andrew J Fisher

Arch Biochem Biophys· September 2009

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Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence.
Mark Wogulis, Erin R Chew, Paul D Donohoue, David K Wilson

Biochemistry· February 2008

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