Publications by authors named "Paul D P Pharoah"

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Comparative validation of PREDICT versions 3.1 and 2.2 for overall survival in the Dutch breast cancer population.
Lara W A Vreven, Elfi M Verheul, Marissa C van Maaren, Frank Doornkamp, Robert-Jan Schipper, Paul D P Pharoah

Breast· December 2025

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Using gene-environment interactions to explore pathways for colorectal cancer risk.
Emmanouil Bouras, Ren Yu, Andre E Kim, Georgios Markozannes, Neil Murphy, Paul D P Pharoah

EBioMedicine· November 2025

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PREDICT breast v4.0: an update to the PREDICT breast prognostic model.
Paul D P Pharoah, Yi-Wen Hsiao, Gordon C Wishart, Pei-Chen Peng

BMC Res Notes· November 2025

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Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.
Daniel R Barnes, Jonathan P Tyrer, Joe Dennis, Goska Leslie, Manjeet K Bolla, Paul D P Pharoah

NPJ Genom Med· November 2025

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S4-Multi: enhancing polygenic score prediction in ancestrally diverse populations.
John Baierl, Jonathan P Tyrer, Ping-Hung Lai, Simon A Gayther, Yi-Wen Hsiao, Paul D P Pharoah

HGG Adv· November 2025

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Adapting the BOADICEA breast and ovarian cancer risk models for the ethnically diverse UK population.
Lorenzo Ficorella, Xin Yang, Nasim Mavaddat, Tim Carver, Hend Hassan, Paul D P Pharoah

Br J Cancer· October 2025

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Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.
Ellen G Engelhardt, Mary Ann E Binuya, Paul D P Pharoah, Coralie Poncet, Emiel J T Rutgers

Breast· October 2025

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Beyond deficiency: Clinical and molecular predictors of survival in patients with -deficient tubo-ovarian high-grade serous carcinoma.
Tibor A Zwimpfer, Sian Fereday, Ahwan Pandey, Dinuka Ariyaratne, Madawa W Jayawardana, Paul D P Pharoah

medRxiv· September 2025

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GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.
Dhanya Ramachandran, Xuemin Wang, Triin Laisk, Ying Zheng, Nathan Ingold, Paul D P Pharoah

EBioMedicine· August 2025

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Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.
Jie Liu, Duc Tran, Liying Xue, Brian J Wiley, Caitlyn Vlasschaert, Paul D P Pharoah

Nat Genet· August 2025

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Ovarian cancer risk and survival according to tumor sex hormone receptor expression: An ovarian Cancer association consortium and ovarian tumor tissue analysis consortium pooled analysis.
Zhuxuan Fu, Lauren Borho, Sarah E Taylor, Linda E Kelemen, Anna DeFazio, Paul D P Pharoah

Gynecol Oncol· July 2025

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Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.
Charlotte Le Cornet, Audrey Y Jung, Sabine Behrens, Pooja Middha, Thérèse Truong, Paul D P Pharoah

JAMA Netw Open· July 2025

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Assessing the Performance of the PREDICT Breast Version 3.0 Prognostic Tool in Patients With Breast Cancer in the United States.
Yi-Wen Hsiao, Gordon C Wishart, Paul D P Pharoah, Pei-Chen Peng

J Natl Compr Canc Netw· May 2025

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Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.
Maria Zanti, Denise G O'Mahony, Michael T Parsons, Leila Dorling, Joe Dennis, Paul D P Pharoah

Nat Commun· May 2025

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Rare germline genetic variation in PAX8 transcription factor binding sites and susceptibility to epithelial ovarian cancer.
Suzana A M Ezquina, Michelle Jones, Ed Dicks, Amber de Vries, Pei-Chen Peng, Paul D P Pharoah

Am J Epidemiol· April 2025

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Polygenic risk scores stratify breast cancer risk among women with benign breast disease.
Mark E Sherman, Stacey J Winham, Robert A Vierkant, Bryan M McCauley, Christopher G Scott, Paul D P Pharoah

J Natl Cancer Inst· March 2025

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Exome sequencing identifies HELB as a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer.
Ed M Dicks, Jonthan P Tyrer, Suzana Ezquina, Michelle Jones, John Baierl, Paul D P Pharoah

Eur J Hum Genet· March 2025

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Interactions Between Genetic and Epidemiological Factors Influencing Mammographic Density.
Austin Hammermeister Suger, Hongjie Chen, Cameron B Haas, Shaoqi Fan, Christopher G Scott, Paul D P Pharoah

Am J Epidemiol· March 2025

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Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer.
Reiner Hoppe, Stefan Winter, Wing-Yee Lo, Kyriaki Michailidou, Manjeet K Bolla, Paul D P Pharoah

NPJ Breast Cancer· February 2025

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Germline copy number variants and endometrial cancer risk.
Cassie E Stylianou, George A R Wiggins, Vanessa L Lau, Joe Dennis, Andrew N Shelling, Paul D P Pharoah

Hum Genet· December 2024

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Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.
Kristia Yiangou, Nasim Mavaddat, Joe Dennis, Maria Zanti, Qin Wang, Paul D P Pharoah

Breast Cancer Res· December 2024

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Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank.
Xin Yang, Yujia Wu, Lorenzo Ficorella, Naomi Wilcox, Joe Dennis, Paul D P Pharoah

Br J Cancer· November 2024

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Analysis of more than 400,000 women provides case-control evidence for and variant classification.
Maria Zanti, Denise G O'Mahony, Michael T Parsons, Leila Dorling, Joe Dennis, Paul D P Pharoah

medRxiv· September 2024

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Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer.
Heather M McGee, Joseph D Bonner, Colt Egelston, Yubo Fu, Oscar Colunga Flores, Paul D P Pharoah

medRxiv· September 2024

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Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer.
Fiona M Blows, H Raza Ali, Wei Cope, Paul D P Pharoah, Claire V S Pike

BJC Rep· January 2024

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